Basic Information
Gene Structure
upstream:
Get Sequence
Domain
| Database | EntryID | E-Value | Start | end | InterPro ID | Description |
|---|
Regulation&Interaction
Annotation
Orthologous Group
| Orthologous ID | Species Number | All hits in PereRegDB | Hits of this species | Orthologous Detail |
|---|
Expression Profile
| DataSet | Number of Samples expressed(TPM>1) | Mean | Min | Max | Standard deviation(SD) | Coeffcient variation(CV) |
|---|
Pathway
| GO Term | Description | GO Category |
|---|---|---|
| GO:0005575 | cellular_component | CC |
| GO:0005622 | intracellular anatomical structure | CC |
| GO:0005623 | obsolete cell | CC |
| GO:0005737 | cytoplasm | CC |
| GO:0005777 | peroxisome | CC |
| GO:0005778 | peroxisomal membrane | CC |
| GO:0005783 | endoplasmic reticulum | CC |
| GO:0005789 | endoplasmic reticulum membrane | CC |
| GO:0006082 | organic acid metabolic process | BP |
| GO:0006629 | lipid metabolic process | BP |
| GO:0006631 | fatty acid metabolic process | BP |
| GO:0006633 | fatty acid biosynthetic process | BP |
| GO:0006996 | organelle organization | BP |
| GO:0007031 | peroxisome organization | BP |
| GO:0008150 | biological_process | BP |
| GO:0008152 | metabolic process | BP |
| GO:0008610 | lipid biosynthetic process | BP |
| GO:0009058 | biosynthetic process | BP |
| GO:0009987 | cellular process | BP |
| GO:0012505 | endomembrane system | CC |
| GO:0016020 | membrane | CC |
| GO:0016043 | cellular component organization | BP |
| GO:0016053 | organic acid biosynthetic process | BP |
| GO:0019752 | carboxylic acid metabolic process | BP |
| GO:0031090 | organelle membrane | CC |
| GO:0031903 | microbody membrane | CC |
| GO:0031984 | organelle subcompartment | CC |
| GO:0032787 | monocarboxylic acid metabolic process | BP |
| GO:0042175 | nuclear outer membrane-endoplasmic reticulum membrane network | CC |
| GO:0042579 | microbody | CC |
| GO:0043226 | organelle | CC |
| GO:0043227 | membrane-bounded organelle | CC |
| GO:0043229 | intracellular organelle | CC |
| GO:0043231 | intracellular membrane-bounded organelle | CC |
| GO:0043436 | oxoacid metabolic process | BP |
| GO:0044237 | cellular metabolic process | BP |
| GO:0044238 | primary metabolic process | BP |
| GO:0044249 | cellular biosynthetic process | BP |
| GO:0044255 | cellular lipid metabolic process | BP |
| GO:0044281 | small molecule metabolic process | BP |
| GO:0044283 | small molecule biosynthetic process | BP |
| GO:0044422 | obsolete organelle part | CC |
| GO:0044424 | obsolete intracellular part | CC |
| GO:0044425 | obsolete membrane part | CC |
| GO:0044432 | obsolete endoplasmic reticulum part | CC |
| GO:0044438 | obsolete microbody part | CC |
| GO:0044439 | obsolete peroxisomal part | CC |
| GO:0044444 | obsolete cytoplasmic part | CC |
| GO:0044446 | obsolete intracellular organelle part | CC |
| GO:0044464 | obsolete cell part | CC |
| GO:0046394 | carboxylic acid biosynthetic process | BP |
| GO:0071704 | organic substance metabolic process | BP |
| GO:0071840 | cellular component organization or biogenesis | BP |
| GO:0072330 | monocarboxylic acid biosynthetic process | BP |
| GO:0098588 | bounding membrane of organelle | CC |
| GO:0098805 | membrane | CC |
| GO:0098827 | endoplasmic reticulum subcompartment | CC |
| GO:1901576 | organic substance biosynthetic process | BP |
| KEGG Term | Name | Description |
|---|---|---|
| map04146 | Peroxisome | Peroxisomes are essential organelles that play a key role in redox signalling and lipid homeostasis. They contribute to many crucial metabolic processes such as fatty acid oxidation, biosynthesis of ether lipids and free radical detoxification. The biogenesis of peroxisomes starts with the early peroxins PEX3, PEX16 and PEX19 and proceeds via several steps. The import of membrane proteins into peroxisomes needs PEX19 for recognition, targeting and insertion via docking at PEX3. Matrix proteins in the cytosol are recognized by peroxisomal targeting signals (PTS) and transported to the docking complex at the peroxisomal membrane. Peroxisomes' deficiencies lead to severe and often fatal inherited peroxisomal disorders (PD). PDs are usually classified in two groups. The first group is disorders of peroxisome biogenesis which include Zellweger syndrome, and the second group is single peroxisomal enzyme deficiencies. |

