Basic Information
Gene Structure
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Domain
| Database | EntryID | E-Value | Start | end | InterPro ID | Description |
|---|
Regulation&Interaction
Annotation
Orthologous Group
| Orthologous ID | Species Number | All hits in PereRegDB | Hits of this species | Orthologous Detail |
|---|
Expression Profile
| DataSet | Number of Samples expressed(TPM>1) | Mean | Min | Max | Standard deviation(SD) | Coeffcient variation(CV) |
|---|
Pathway
| GO Term | Description | GO Category |
|---|---|---|
| GO:0003674 | molecular_function | MF |
| GO:0005488 | binding | MF |
| GO:0005515 | protein binding | MF |
| GO:0005575 | cellular_component | CC |
| GO:0005622 | intracellular anatomical structure | CC |
| GO:0005623 | obsolete cell | CC |
| GO:0005737 | cytoplasm | CC |
| GO:0005777 | peroxisome | CC |
| GO:0005778 | peroxisomal membrane | CC |
| GO:0005779 | obsolete integral component of peroxisomal membrane | CC |
| GO:0005911 | cell-cell junction | CC |
| GO:0006996 | organelle organization | BP |
| GO:0007031 | peroxisome organization | BP |
| GO:0008150 | biological_process | BP |
| GO:0009506 | plasmodesma | CC |
| GO:0009987 | cellular process | BP |
| GO:0016020 | membrane | CC |
| GO:0016021 | membrane | CC |
| GO:0016043 | cellular component organization | BP |
| GO:0016559 | peroxisome fission | BP |
| GO:0030054 | cell junction | CC |
| GO:0031090 | organelle membrane | CC |
| GO:0031224 | obsolete intrinsic component of membrane | CC |
| GO:0031231 | obsolete intrinsic component of peroxisomal membrane | CC |
| GO:0031300 | obsolete intrinsic component of organelle membrane | CC |
| GO:0031301 | obsolete integral component of organelle membrane | CC |
| GO:0031903 | microbody membrane | CC |
| GO:0032535 | regulation of cellular component size | BP |
| GO:0042579 | microbody | CC |
| GO:0042802 | identical protein binding | MF |
| GO:0043226 | organelle | CC |
| GO:0043227 | membrane-bounded organelle | CC |
| GO:0043229 | intracellular organelle | CC |
| GO:0043231 | intracellular membrane-bounded organelle | CC |
| GO:0044375 | regulation of peroxisome size | BP |
| GO:0044422 | obsolete organelle part | CC |
| GO:0044424 | obsolete intracellular part | CC |
| GO:0044425 | obsolete membrane part | CC |
| GO:0044438 | obsolete microbody part | CC |
| GO:0044439 | obsolete peroxisomal part | CC |
| GO:0044444 | obsolete cytoplasmic part | CC |
| GO:0044446 | obsolete intracellular organelle part | CC |
| GO:0044464 | obsolete cell part | CC |
| GO:0048285 | organelle fission | BP |
| GO:0055044 | symplast | CC |
| GO:0065007 | biological regulation | BP |
| GO:0065008 | regulation of biological quality | BP |
| GO:0071840 | cellular component organization or biogenesis | BP |
| GO:0090066 | regulation of anatomical structure size | BP |
| GO:0098588 | bounding membrane of organelle | CC |
| GO:0098805 | membrane | CC |
| KEGG Term | Name | Description |
|---|---|---|
| map04146 | Peroxisome | Peroxisomes are essential organelles that play a key role in redox signalling and lipid homeostasis. They contribute to many crucial metabolic processes such as fatty acid oxidation, biosynthesis of ether lipids and free radical detoxification. The biogenesis of peroxisomes starts with the early peroxins PEX3, PEX16 and PEX19 and proceeds via several steps. The import of membrane proteins into peroxisomes needs PEX19 for recognition, targeting and insertion via docking at PEX3. Matrix proteins in the cytosol are recognized by peroxisomal targeting signals (PTS) and transported to the docking complex at the peroxisomal membrane. Peroxisomes' deficiencies lead to severe and often fatal inherited peroxisomal disorders (PD). PDs are usually classified in two groups. The first group is disorders of peroxisome biogenesis which include Zellweger syndrome, and the second group is single peroxisomal enzyme deficiencies. |