PPGR - Gene Detail

Basic Information

Gene ID	FRAEX38873_v2_000396800 View in Genome Browser
Position	Contig980:157128-159224 (+) 2096bp
Gene Type	gene
Gene Description (Protein Product)	"Ubiquitin exists either covalently attached to another protein
Organism	Fraxinus excelsior
Also AS	AT4G05320

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Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)

FRAEX38873_v2_000396800 Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked

FRAEX38873_v2_000398590 Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain

FRAEX38873_v2_000397450 Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Expression Profile

DataSet	Number of Samples expressed(TPM>1)	Mean	Min	Max	Standard deviation(SD)	Coeffcient variation(CV)

Select Expression

Pathway

GO Term	Description	GO Category
GO:0001101	response to acid chemical	BP
GO:0006464	protein modification process	BP
GO:0006807	nitrogen compound metabolic process	BP
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0009719	response to endogenous stimulus	BP
GO:0009725	response to hormone	BP
GO:0009751	response to salicylic acid	BP
GO:0009987	cellular process	BP
GO:0010033	response to organic substance	BP
GO:0014070	response to organic cyclic compound	BP
GO:0019538	protein metabolic process	BP
GO:0036211	protein modification process	BP
GO:0042221	response to chemical	BP
GO:0042493	response to xenobiotic stimulus	BP
GO:0043170	macromolecule metabolic process	BP
GO:0043412	macromolecule modification	BP
GO:0044237	cellular metabolic process	BP
GO:0044238	primary metabolic process	BP
GO:0044260	cellular macromolecule metabolic process	BP
GO:0044267	protein metabolic process	BP
GO:0046677	response to antibiotic	BP
GO:0050896	response to stimulus	BP
GO:0071704	organic substance metabolic process	BP
GO:1901564	organonitrogen compound metabolic process	BP
GO:1901700	response to oxygen-containing compound	BP

KEGG Term	Name	Description
map04120	Ubiquitin mediated proteolysis	Protein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to proteins being degraded is performed by a reaction cascade consisting of three enzymes, named E1 (ubiquitin activating enzyme), E2 (ubiquitin conjugating enzyme), and E3 (ubiquitin ligase). Each E3 has specificity to its substrate, or proteins to be targeted by ubiquitination. Many E3s are discovered in eukaryotes and they are classified into four types: HECT type, U-box type, single RING-finger type, and multi-subunit RING-finger type. Multi-subunit RING-finger E3s are exemplified by cullin-Rbx E3s and APC/C. They consist of a RING-finger-containing subunit (RBX1 or RBX2) that functions to bind E2s, a scaffold-like cullin molecule, adaptor proteins, and a target recognizing subunit that binds substrates.