Basic Information
Gene ID
JhiChr06G11175.g
Position
chr6:17015956-17024443 (+)
8487bp
Gene Type
gene
Gene Description (Protein Product)
RNA-binding protein
Organism
Also AS AT1G60200

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
JhiChr13G10245.g Small nuclear ribonucleoprotein-associated protein
JhiChr10G10027.g splicing factor 3A subunit
JhiChr07G11479.g Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
GO Term Description GO Category
GO:0000381 regulation of alternative mRNA splicing, via spliceosome BP
GO:0003674 molecular_function MF
GO:0003676 nucleic acid binding MF
GO:0003723 RNA binding MF
GO:0003729 mRNA binding MF
GO:0005488 binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005654 nucleoplasm CC
GO:0005681 spliceosomal complex CC
GO:0005737 cytoplasm CC
GO:0008150 biological_process BP
GO:0010468 regulation of gene expression BP
GO:0010941 regulation of cell death BP
GO:0016604 nuclear body CC
GO:0016607 nuclear speck CC
GO:0019219 regulation of nucleobase-containing compound metabolic process BP
GO:0019222 regulation of metabolic process BP
GO:0031323 regulation of cellular metabolic process BP
GO:0031974 membrane-enclosed lumen CC
GO:0031981 nuclear lumen CC
GO:0032991 protein-containing complex CC
GO:0042981 regulation of apoptotic process BP
GO:0043067 regulation of programmed cell death BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043233 organelle lumen CC
GO:0043484 regulation of RNA splicing BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044428 obsolete nuclear part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044451 obsolete nucleoplasm part CC
GO:0044464 obsolete cell part CC
GO:0048024 regulation of mRNA splicing, via spliceosome BP
GO:0050684 regulation of mRNA processing BP
GO:0050789 regulation of biological process BP
GO:0050794 regulation of cellular process BP
GO:0051171 regulation of nitrogen compound metabolic process BP
GO:0051252 regulation of RNA metabolic process BP
GO:0060255 regulation of macromolecule metabolic process BP
GO:0065007 biological regulation BP
GO:0070013 intracellular organelle lumen CC
GO:0080090 regulation of primary metabolic process BP
GO:0097159 organic cyclic compound binding MF
GO:1901363 heterocyclic compound binding MF
GO:1903311 regulation of mRNA metabolic process BP
GO:1990904 ribonucleoprotein complex CC
KEGG Term Name Description
map03040 Spliceosome After transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, the spliceosome. The standard spliceosome is made up of five small nuclear ribonucleoproteins (snRNPs), U1, U2, U4, U5, and U6 snRNPs, and several spliceosome-associated proteins (SAPs). Spliceosomes are not a simple stable complex, but a dynamic family of particles that assemble on the mRNA precursor and help fold it into a conformation that allows transesterification to proceed. Various spliceosome forms (e.g. A-, B- and C-complexes) have been identified.