Basic Information
Gene ID
JhiChr12G10478.g
Position
chr12:9544787-9548478 (-)
3691bp
Gene Type
gene
Gene Description (Protein Product)
Serine threonine-protein kinase
Organism
Also AS AT3G48187

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
JhiChr16G10737.g DNA topoisomerase 2-binding protein
JhiChr13G10784.g Crossover junction endonuclease
JhiChr12G11364.g DNA polymerase delta
Regulatory gene
JhiChr01G10740.g Zinc-finger homeodomain protein
JhiChr01G10819.g dof zinc finger protein
JhiChr01G11113.g ZF-HD protein dimerisation region

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
KEGG Term Name Description
map03440 Homologous recombination Homologous recombination (HR) is essential for the accurate repair of DNA double-strand breaks (DSBs), potentially lethal lesions. HR takes place in the late S-G2 phase of the cell cycle and involves the generation of a single-stranded region of DNA, followed by strand invasion, formation of a Holliday junction, DNA synthesis using the intact strand as a template, branch migration and resolution. It is investigated that RecA/Rad51 family proteins play a central role. The breast cancer susceptibility protein Brca2 and the RecQ helicase BLM (Bloom syndrome mutated) are tumor suppressors that maintain genome integrity, at least in part, through HR.