Basic Information
Gene Structure
Domain
Regulation&
Interaction
Annotation
Orthologus Group
Pathway
Basic Information
Gene ID
JhiChr13G10784.g
View in Genome Browser
Position
chr13:879835-885947 (+)
6112bp
Gene Type
gene
Gene Description (Protein Product)
Crossover junction endonuclease
Organism
Juglans hindsii
Also AS AT4G30870

Gene Structure

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Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
JhiChr14G10545.g Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA
JhiChr13G11723.g Ribonuclease P protein subunit
JhiChr14G10054.g Structural maintenance of chromosomes protein
Regulatory gene
JhiChr01G10819.g dof zinc finger protein
JhiChr01G11697.g dof zinc finger protein
JhiChr01G12868.g Dof zinc finger protein

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
Go Pathway KEGG Pathway
GO Term Description GO Category
GO:0000003 reproduction BP
GO:0000075 cell cycle checkpoint signaling BP
GO:0000077 DNA damage checkpoint signaling BP
GO:0000228 nuclear chromosome CC
GO:0000278 mitotic cell cycle BP
GO:0000280 nuclear division BP
GO:0000712 resolution of meiotic recombination intermediates BP
GO:0000724 double-strand break repair via homologous recombination BP
GO:0000725 recombinational repair BP
GO:0000727 double-strand break repair via break-induced replication BP
GO:0000793 condensed chromosome CC
GO:0000794 condensed nuclear chromosome CC
GO:0003674 molecular_function MF
GO:0003824 catalytic activity MF
GO:0004518 nuclease activity MF
GO:0004519 endonuclease activity MF
GO:0004520 DNA endonuclease activity MF
GO:0004536 deoxyribonuclease activity MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005694 chromosome CC
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006259 DNA metabolic process BP
GO:0006260 DNA replication BP
GO:0006261 DNA-templated DNA replication BP
GO:0006281 DNA repair BP
GO:0006302 double-strand break repair BP
GO:0006310 DNA recombination BP
GO:0006312 mitotic recombination BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006950 response to stress BP
GO:0006974 cellular response to DNA damage stimulus BP
GO:0006996 organelle organization BP
GO:0007049 cell cycle BP
GO:0007059 chromosome segregation BP
GO:0007093 mitotic cell cycle checkpoint signaling BP
GO:0007095 mitotic G2 DNA damage checkpoint signaling BP
GO:0007127 meiosis I BP
GO:0007129 homologous chromosome pairing at meiosis BP
GO:0007131 reciprocal meiotic recombination BP
GO:0007346 regulation of mitotic cell cycle BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009058 biosynthetic process BP
GO:0009059 macromolecule biosynthetic process BP
GO:0009987 cellular process BP
GO:0010389 regulation of G2/M transition of mitotic cell cycle BP
GO:0010564 regulation of cell cycle process BP
GO:0010948 negative regulation of cell cycle process BP
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle BP
GO:0016043 cellular component organization BP
GO:0016787 hydrolase activity MF
GO:0016788 hydrolase activity, acting on ester bonds MF
GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters MF
GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters MF
GO:0022402 cell cycle process BP
GO:0022414 reproductive process BP
GO:0022607 cellular component assembly BP
GO:0031297 replication fork processing BP
GO:0031570 DNA integrity checkpoint signaling BP
GO:0031572 mitotic G2 DNA damage checkpoint signaling BP
GO:0031573 mitotic intra-S DNA damage checkpoint signaling BP
GO:0031974 membrane-enclosed lumen CC
GO:0031981 nuclear lumen CC
GO:0032991 protein-containing complex CC
GO:0033554 cellular response to stress BP
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0034645 cellular macromolecule biosynthetic process BP
GO:0035825 homologous recombination BP
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043228 non-membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043232 intracellular non-membrane-bounded organelle CC
GO:0043233 organelle lumen CC
GO:0044085 cellular component biogenesis BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044249 cellular biosynthetic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044428 obsolete nuclear part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044464 obsolete cell part CC
GO:0044773 mitotic DNA damage checkpoint signaling BP
GO:0044774 mitotic DNA integrity checkpoint signaling BP
GO:0044818 mitotic G2/M transition checkpoint BP
GO:0045005 DNA-templated DNA replication maintenance of fidelity BP
GO:0045132 meiotic chromosome segregation BP
GO:0045143 homologous chromosome segregation BP
GO:0045786 negative regulation of cell cycle BP
GO:0045930 negative regulation of mitotic cell cycle BP
GO:0046483 heterocycle metabolic process BP
GO:0048256 flap endonuclease activity MF
GO:0048257 3'-flap endonuclease activity MF
GO:0048285 organelle fission BP
GO:0048476 Holliday junction resolvase complex CC
GO:0048519 negative regulation of biological process BP
GO:0048523 negative regulation of cellular process BP
GO:0050789 regulation of biological process BP
GO:0050794 regulation of cellular process BP
GO:0050896 response to stimulus BP
GO:0051026 chiasma assembly BP
GO:0051276 chromosome organization BP
GO:0051304 chromosome separation BP
GO:0051307 meiotic chromosome separation BP
GO:0051321 meiotic cell cycle BP
GO:0051716 cellular response to stimulus BP
GO:0051726 regulation of cell cycle BP
GO:0061982 meiosis I cell cycle process BP
GO:0065007 biological regulation BP
GO:0070013 intracellular organelle lumen CC
GO:0070192 chromosome organization involved in meiotic cell cycle BP
GO:0071704 organic substance metabolic process BP
GO:0071840 cellular component organization or biogenesis BP
GO:0090304 nucleic acid metabolic process BP
GO:0090305 nucleic acid phosphodiester bond hydrolysis BP
GO:0098813 nuclear chromosome segregation BP
GO:0140013 meiotic nuclear division BP
GO:0140097 catalytic activity, acting on DNA MF
GO:1901360 organic cyclic compound metabolic process BP
GO:1901576 organic substance biosynthetic process BP
GO:1901987 regulation of cell cycle phase transition BP
GO:1901988 negative regulation of cell cycle phase transition BP
GO:1901990 regulation of mitotic cell cycle phase transition BP
GO:1901991 negative regulation of mitotic cell cycle phase transition BP
GO:1902749 regulation of cell cycle G2/M phase transition BP
GO:1902750 negative regulation of cell cycle G2/M phase transition BP
GO:1903046 meiotic cell cycle process BP
GO:1903047 mitotic cell cycle process BP
KEGG Term Name Description
map03440 Homologous recombination Homologous recombination (HR) is essential for the accurate repair of DNA double-strand breaks (DSBs), potentially lethal lesions. HR takes place in the late S-G2 phase of the cell cycle and involves the generation of a single-stranded region of DNA, followed by strand invasion, formation of a Holliday junction, DNA synthesis using the intact strand as a template, branch migration and resolution. It is investigated that RecA/Rad51 family proteins play a central role. The breast cancer susceptibility protein Brca2 and the RecQ helicase BLM (Bloom syndrome mutated) are tumor suppressors that maintain genome integrity, at least in part, through HR.