Basic Information
Gene Structure
upstream:
Get Sequence
Domain
| Database | EntryID | E-Value | Start | end | InterPro ID | Description |
|---|
Regulation&Interaction
Annotation
Orthologous Group
| Orthologous ID | Species Number | All hits in PereRegDB | Hits of this species | Orthologous Detail |
|---|
Expression Profile
| DataSet | Number of Samples expressed(TPM>1) | Mean | Min | Max | Standard deviation(SD) | Coeffcient variation(CV) |
|---|
Pathway
| GO Term | Description | GO Category |
|---|---|---|
| GO:0001676 | long-chain fatty acid metabolic process | BP |
| GO:0003674 | molecular_function | MF |
| GO:0003824 | catalytic activity | MF |
| GO:0004467 | long-chain fatty acid-CoA ligase activity | MF |
| GO:0005575 | cellular_component | CC |
| GO:0005622 | intracellular anatomical structure | CC |
| GO:0005623 | obsolete cell | CC |
| GO:0005737 | cytoplasm | CC |
| GO:0005783 | endoplasmic reticulum | CC |
| GO:0005794 | Golgi apparatus | CC |
| GO:0005886 | plasma membrane | CC |
| GO:0006082 | organic acid metabolic process | BP |
| GO:0006629 | lipid metabolic process | BP |
| GO:0006631 | fatty acid metabolic process | BP |
| GO:0008150 | biological_process | BP |
| GO:0008152 | metabolic process | BP |
| GO:0009987 | cellular process | BP |
| GO:0012505 | endomembrane system | CC |
| GO:0015645 | fatty acid ligase activity | MF |
| GO:0016020 | membrane | CC |
| GO:0016405 | CoA-ligase activity | MF |
| GO:0016874 | ligase activity | MF |
| GO:0016877 | ligase activity, forming carbon-sulfur bonds | MF |
| GO:0016878 | acid-thiol ligase activity | MF |
| GO:0019752 | carboxylic acid metabolic process | BP |
| GO:0032787 | monocarboxylic acid metabolic process | BP |
| GO:0043226 | organelle | CC |
| GO:0043227 | membrane-bounded organelle | CC |
| GO:0043229 | intracellular organelle | CC |
| GO:0043231 | intracellular membrane-bounded organelle | CC |
| GO:0043436 | oxoacid metabolic process | BP |
| GO:0044237 | cellular metabolic process | BP |
| GO:0044238 | primary metabolic process | BP |
| GO:0044255 | cellular lipid metabolic process | BP |
| GO:0044281 | small molecule metabolic process | BP |
| GO:0044424 | obsolete intracellular part | CC |
| GO:0044444 | obsolete cytoplasmic part | CC |
| GO:0044464 | obsolete cell part | CC |
| GO:0071704 | organic substance metabolic process | BP |
| GO:0071944 | cell periphery | CC |
| KEGG Term | Name | Description |
|---|---|---|
| map04146 | Peroxisome | Peroxisomes are essential organelles that play a key role in redox signalling and lipid homeostasis. They contribute to many crucial metabolic processes such as fatty acid oxidation, biosynthesis of ether lipids and free radical detoxification. The biogenesis of peroxisomes starts with the early peroxins PEX3, PEX16 and PEX19 and proceeds via several steps. The import of membrane proteins into peroxisomes needs PEX19 for recognition, targeting and insertion via docking at PEX3. Matrix proteins in the cytosol are recognized by peroxisomal targeting signals (PTS) and transported to the docking complex at the peroxisomal membrane. Peroxisomes' deficiencies lead to severe and often fatal inherited peroxisomal disorders (PD). PDs are usually classified in two groups. The first group is disorders of peroxisome biogenesis which include Zellweger syndrome, and the second group is single peroxisomal enzyme deficiencies. |
| map01100 | Metabolic pathways | - |
| map00071 | Fatty acid metabolism | - |
| map00061 | Fatty acid biosynthesis | - |