Basic Information
Gene Structure
Domain
Regulation&
Interaction
Annotation
Orthologus Group
Expresssion
Pathway
Basic Information
Gene ID
PtQG43010
View in Genome Browser
Position
chr12:1363193035-1363332242 (-)
139207bp
Gene Type
gene
Gene Description (Protein Product)
E3 ubiquitin protein ligase
Organism
Pinus tabuliformis
Also AS AT4G25230

Gene Structure

upstream:
Get Sequence

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
PtXG02490 May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins
PtQG43010 E3 ubiquitin protein ligase
PtXG17930 Ubiquitin family
Regulatory gene
Pt6G52280 Tesmin/TSO1-like CXC domain
Pt7G39150 tesmin TSO1-like CXC

Load All Networks

Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail

Expression Profile
DataSet Number of Samples expressed(TPM>1) Mean Min Max Standard deviation(SD) Coeffcient variation(CV)


Pathway
Go Pathway KEGG Pathway
GO Term Description GO Category
GO:0000209 protein polyubiquitination BP
GO:0002682 regulation of immune system process BP
GO:0002684 positive regulation of immune system process BP
GO:0003674 molecular_function MF
GO:0003824 catalytic activity MF
GO:0004842 ubiquitin-protein transferase activity MF
GO:0005575 cellular_component CC
GO:0005623 obsolete cell CC
GO:0005886 plasma membrane CC
GO:0006464 protein modification process BP
GO:0006508 proteolysis BP
GO:0006511 ubiquitin-dependent protein catabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009056 catabolic process BP
GO:0009057 macromolecule catabolic process BP
GO:0009987 cellular process BP
GO:0010363 regulation of plant-type hypersensitive response BP
GO:0010498 proteasomal protein catabolic process BP
GO:0010941 regulation of cell death BP
GO:0010942 positive regulation of cell death BP
GO:0016020 membrane CC
GO:0016567 protein ubiquitination BP
GO:0016740 transferase activity MF
GO:0019538 protein metabolic process BP
GO:0019787 ubiquitin-like protein transferase activity MF
GO:0019941 modification-dependent protein catabolic process BP
GO:0030163 protein catabolic process BP
GO:0031347 regulation of defense response BP
GO:0031349 positive regulation of defense response BP
GO:0032446 protein modification by small protein conjugation BP
GO:0034052 positive regulation of plant-type hypersensitive response BP
GO:0036211 protein modification process BP
GO:0043067 regulation of programmed cell death BP
GO:0043068 positive regulation of programmed cell death BP
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process BP
GO:0043170 macromolecule metabolic process BP
GO:0043412 macromolecule modification BP
GO:0043632 modification-dependent macromolecule catabolic process BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044248 cellular catabolic process BP
GO:0044257 protein catabolic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044265 cellular macromolecule catabolic process BP
GO:0044267 protein metabolic process BP
GO:0044464 obsolete cell part CC
GO:0045088 regulation of innate immune response BP
GO:0045089 positive regulation of innate immune response BP
GO:0048518 positive regulation of biological process BP
GO:0048522 positive regulation of cellular process BP
GO:0048583 regulation of response to stimulus BP
GO:0048584 positive regulation of response to stimulus BP
GO:0050776 regulation of immune response BP
GO:0050778 positive regulation of immune response BP
GO:0050789 regulation of biological process BP
GO:0050794 regulation of cellular process BP
GO:0051603 proteolysis involved in protein catabolic process BP
GO:0061630 ubiquitin protein ligase activity MF
GO:0061659 ubiquitin-like protein ligase activity MF
GO:0065007 biological regulation BP
GO:0070647 protein modification by small protein conjugation or removal BP
GO:0071704 organic substance metabolic process BP
GO:0071944 cell periphery CC
GO:0080134 regulation of response to stress BP
GO:0080135 regulation of cellular response to stress BP
GO:0140096 catalytic activity, acting on a protein MF
GO:1901564 organonitrogen compound metabolic process BP
GO:1901565 organonitrogen compound catabolic process BP
GO:1901575 organic substance catabolic process BP
KEGG Term Name Description
map04141 Protein processing in endoplasmic reticulum The endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylated. Correctly folded proteins are packaged into transport vesicles that shuttle them to the Golgi complex. Misfolded proteins are retained within the ER lumen in complex with molecular chaperones. Proteins that are terminally misfolded bind to BiP and are directed toward degradation through the proteasome in a process called ER-associated degradation (ERAD). Accumulation of misfolded proteins in the ER causes ER stress and activates a signaling pathway called the unfolded protein response (UPR). In certain severe situations, however, the protective mechanisms activated by the UPR are not sufficient to restore normal ER function and cells die by apoptosis.