PPGR - Gene Detail

Basic Information

Gene Structure

Domain

Regulation&
Interaction

Annotation

Orthologus Group

Expresssion

Pathway

Basic Information

Gene ID	PtXG40280 View in Genome Browser
Position	chr10:1246933990-1247153253 (+) 219263bp
Gene Type	gene
Gene Description (Protein Product)	Gpi-anchor transamidase Gpi-anchor
Organism	Pinus tabuliformis
Also AS	AT1G08750

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Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)	PtXG40280 Gpi-anchor transamidase PtXG40280 Gpi-anchor PtXG44840 MADS-box protein
Regulatory gene	Pt0G01630 dof zinc finger protein Pt0G07980 dof zinc finger protein Pt0G30790 Myb family transcription factor

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Expression Profile

DataSet	Number of Samples expressed(TPM>1)	Mean	Min	Max	Standard deviation(SD)	Coeffcient variation(CV)

Select Expression

Pathway

GO Term	Description	GO Category
GO:0003674	molecular_function	MF
GO:0003824	catalytic activity	MF
GO:0003923	GPI-anchor transamidase activity	MF
GO:0005575	cellular_component	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005737	cytoplasm	CC
GO:0005783	endoplasmic reticulum	CC
GO:0005789	endoplasmic reticulum membrane	CC
GO:0006464	protein modification process	BP
GO:0006497	protein lipidation	BP
GO:0006505	GPI anchor metabolic process	BP
GO:0006506	GPI anchor biosynthetic process	BP
GO:0006629	lipid metabolic process	BP
GO:0006643	membrane lipid metabolic process	BP
GO:0006644	phospholipid metabolic process	BP
GO:0006650	glycerophospholipid metabolic process	BP
GO:0006661	phosphatidylinositol biosynthetic process	BP
GO:0006664	glycolipid metabolic process	BP
GO:0006793	phosphorus metabolic process	BP
GO:0006796	phosphate-containing compound metabolic process	BP
GO:0006807	nitrogen compound metabolic process	BP
GO:0008104	protein localization	BP
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0008610	lipid biosynthetic process	BP
GO:0008654	phospholipid biosynthetic process	BP
GO:0009058	biosynthetic process	BP
GO:0009059	macromolecule biosynthetic process	BP
GO:0009247	glycolipid biosynthetic process	BP
GO:0009987	cellular process	BP
GO:0012505	endomembrane system	CC
GO:0016020	membrane	CC
GO:0016021	membrane	CC
GO:0016255	attachment of GPI anchor to protein	BP
GO:0016787	hydrolase activity	MF
GO:0019538	protein metabolic process	BP
GO:0019637	organophosphate metabolic process	BP
GO:0030176	obsolete integral component of endoplasmic reticulum membrane	CC
GO:0031224	obsolete intrinsic component of membrane	CC
GO:0031227	obsolete intrinsic component of endoplasmic reticulum membrane	CC
GO:0031984	organelle subcompartment	CC
GO:0032991	protein-containing complex	CC
GO:0033036	macromolecule localization	BP
GO:0034394	protein localization to cell surface	BP
GO:0034613	protein localization	BP
GO:0034645	cellular macromolecule biosynthetic process	BP
GO:0036211	protein modification process	BP
GO:0042157	lipoprotein metabolic process	BP
GO:0042158	lipoprotein biosynthetic process	BP
GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network	CC
GO:0042765	GPI-anchor transamidase complex	CC
GO:0043170	macromolecule metabolic process	BP
GO:0043226	organelle	CC
GO:0043227	membrane-bounded organelle	CC
GO:0043229	intracellular organelle	CC
GO:0043231	intracellular membrane-bounded organelle	CC
GO:0043412	macromolecule modification	BP
GO:0044237	cellular metabolic process	BP
GO:0044238	primary metabolic process	BP
GO:0044249	cellular biosynthetic process	BP
GO:0044255	cellular lipid metabolic process	BP
GO:0044260	cellular macromolecule metabolic process	BP
GO:0044267	protein metabolic process	BP
GO:0044422	obsolete organelle part	CC
GO:0044424	obsolete intracellular part	CC
GO:0044425	obsolete membrane part	CC
GO:0044432	obsolete endoplasmic reticulum part	CC
GO:0044444	obsolete cytoplasmic part	CC
GO:0044446	obsolete intracellular organelle part	CC
GO:0044464	obsolete cell part	CC
GO:0045017	glycerolipid biosynthetic process	BP
GO:0046467	membrane lipid biosynthetic process	BP
GO:0046474	glycerophospholipid biosynthetic process	BP
GO:0046486	glycerolipid metabolic process	BP
GO:0046488	phosphatidylinositol metabolic process	BP
GO:0051179	localization	BP
GO:0051641	cellular localization	BP
GO:0070727	cellular macromolecule localization	BP
GO:0071704	organic substance metabolic process	BP
GO:0090407	organophosphate biosynthetic process	BP
GO:0098796	membrane protein complex	CC
GO:0098827	endoplasmic reticulum subcompartment	CC
GO:0140096	catalytic activity, acting on a protein	MF
GO:1901135	carbohydrate derivative metabolic process	BP
GO:1901137	carbohydrate derivative biosynthetic process	BP
GO:1901564	organonitrogen compound metabolic process	BP
GO:1901566	organonitrogen compound biosynthetic process	BP
GO:1901576	organic substance biosynthetic process	BP
GO:1902494	catalytic complex	CC
GO:1903509	liposaccharide metabolic process	BP

KEGG Term	Name	Description
map01100	Metabolic pathways	-
map00563	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis	Cell surface proteins can be attached to the cell membrane via the glycolipid structure called glycosylphosphatidylinositol (GPI) anchor. Hundreds of GPI-anchored proteins have been identified in many eukaryotes ranging from protozoa and fungi to mammals. All protein-linked GPI anchors share a common core structure, characterized by the substructure Man (a1-4) GlcN (a1-6) myo-inositol-1P-lipid. Biosynthesis of GPI anchors proceeds in three stages: (i) preassembly of a GPI precursor in the ER membrane, (ii) attachment of the GPI to the C-terminus of a newly synthesized protein in the lumen of the ER, and (iii) lipid remodeling and/or carbohydrate side-chain modifications in the ER and the Golgi. Defects of GPI anchor biosynthesis gene result in a genetic disorder, paroxysmal nocturnal hemoglobinuria.