Basic Information
Gene ID
Position
chr10:1518418540-1518419869 (-)
1329bp
Gene Type
gene
Gene Description (Protein Product)
GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle
Organism
Also AS AT5G55190

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
PtXG48500 GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle
PtXG52550 60S ribosomal Protein
PtXG52360 60S ribosomal Protein
Regulatory gene
Pt0G01110 Myb-like DNA-binding domain
Pt0G06240 Transcription factor

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail

Expression Profile
DataSet Number of Samples expressed(TPM>1) Mean Min Max Standard deviation(SD) Coeffcient variation(CV)


Pathway
GO Term Description GO Category
GO:0000054 ribosomal subunit export from nucleus BP
GO:0000166 nucleotide binding MF
GO:0001882 nucleoside binding MF
GO:0001883 purine nucleoside binding MF
GO:0003674 molecular_function MF
GO:0003824 catalytic activity MF
GO:0003924 GTPase activity MF
GO:0005488 binding MF
GO:0005525 GTP binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005730 nucleolus CC
GO:0005737 cytoplasm CC
GO:0005794 Golgi apparatus CC
GO:0006403 RNA localization BP
GO:0006405 RNA export from nucleus BP
GO:0006606 protein import into nucleus BP
GO:0006611 protein export from nucleus BP
GO:0006810 transport BP
GO:0006886 intracellular protein transport BP
GO:0006913 nucleocytoplasmic transport BP
GO:0008104 protein localization BP
GO:0008150 biological_process BP
GO:0010035 response to inorganic substance BP
GO:0010038 response to metal ion BP
GO:0012505 endomembrane system CC
GO:0015031 protein transport BP
GO:0015833 peptide transport BP
GO:0015931 nucleobase-containing compound transport BP
GO:0016462 pyrophosphatase activity MF
GO:0016787 hydrolase activity MF
GO:0016817 hydrolase activity, acting on acid anhydrides MF
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides MF
GO:0017038 protein import BP
GO:0017076 purine nucleotide binding MF
GO:0017111 ribonucleoside triphosphate phosphatase activity MF
GO:0019001 guanyl nucleotide binding MF
GO:0022613 ribonucleoprotein complex biogenesis BP
GO:0031503 protein-containing complex localization BP
GO:0031974 membrane-enclosed lumen CC
GO:0031981 nuclear lumen CC
GO:0032549 ribonucleoside binding MF
GO:0032550 purine ribonucleoside binding MF
GO:0032553 ribonucleotide binding MF
GO:0032555 purine ribonucleotide binding MF
GO:0032561 guanyl ribonucleotide binding MF
GO:0033036 macromolecule localization BP
GO:0033365 protein localization to organelle BP
GO:0033750 ribosome localization BP
GO:0034504 protein localization to nucleus BP
GO:0034613 protein localization BP
GO:0035639 purine ribonucleoside triphosphate binding MF
GO:0036094 small molecule binding MF
GO:0042221 response to chemical BP
GO:0042254 ribosome biogenesis BP
GO:0042886 amide transport BP
GO:0043167 ion binding MF
GO:0043168 anion binding MF
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043228 non-membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043232 intracellular non-membrane-bounded organelle CC
GO:0043233 organelle lumen CC
GO:0044085 cellular component biogenesis BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044428 obsolete nuclear part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044464 obsolete cell part CC
GO:0045184 establishment of protein localization BP
GO:0046686 response to cadmium ion BP
GO:0046907 intracellular transport BP
GO:0050657 nucleic acid transport BP
GO:0050658 RNA transport BP
GO:0050896 response to stimulus BP
GO:0051168 nuclear export BP
GO:0051169 nuclear transport BP
GO:0051170 import into nucleus BP
GO:0051179 localization BP
GO:0051234 establishment of localization BP
GO:0051236 establishment of RNA localization BP
GO:0051640 organelle localization BP
GO:0051641 cellular localization BP
GO:0051649 establishment of localization in cell BP
GO:0051656 establishment of organelle localization BP
GO:0070013 intracellular organelle lumen CC
GO:0070727 cellular macromolecule localization BP
GO:0071166 ribonucleoprotein complex localization BP
GO:0071426 obsolete ribonucleoprotein complex export from nucleus BP
GO:0071428 obsolete rRNA-containing ribonucleoprotein complex export from nucleus BP
GO:0071702 organic substance transport BP
GO:0071705 nitrogen compound transport BP
GO:0071840 cellular component organization or biogenesis BP
GO:0072594 establishment of protein localization to organelle BP
GO:0097159 organic cyclic compound binding MF
GO:0097367 carbohydrate derivative binding MF
GO:1901265 nucleoside phosphate binding MF
GO:1901363 heterocyclic compound binding MF
KEGG Term Name Description
map03013 RNA transport RNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) via mobile export receptors. The majority of RNAs, such as tRNAs, rRNAs, and U snRNAs, are transported by specific export receptors, which belong to the karyopherin-beta family proteins. A feature of karyopherins is their regulation by the small GTPase Ran. However, general mRNA export is mechanistically different. Nuclear export of mRNAs is functionally coupled to different steps in gene expression processes, such as transcription, splicing, 3'-end formation and even translation.
map03008 Ribosome biogenesis in eukaryotes Ribosomes are the cellular factories responsible for making proteins. In eukaryotes, ribosome biogenesis involves the production and correct assembly of four rRNAs and about 80 ribosomal proteins. It requires hundreds of factors not present in the mature particle. In the absence of these proteins, ribosome biogenesis is stalled and cell growth is terminated even under optimal growth conditions. The primary pre-rRNA transcript is assembled into the 90S pre-ribosome, which contains both 40S and 60S assembly factors. Within this complex, the pre-rRNA is cleaved. pre-60S ribosomes are subjected to several sequential processing steps in the nucleoplasm involving numerous assembly intermediates before it is exported to the cytoplasm and matured into the 60S ribosomal subunit. The pre-40S ribosome is matured to the small ribosomal subunit in the cytoplasm by cleavage.