PPGR - Gene Detail

Basic Information

Gene ID	gene-GBA52_020259 View in Genome Browser
Position	CM035465.1:16715815-16728684 (-) 12869bp
Gene Type	gene
Gene Description (Protein Product)	Crossover junction endonuclease
Organism	Prunus armeniaca
Also AS	MD15G1335700AT2G22140PRUPE_6G166800

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)

gene-GBA52_024834 Crossover junction endonuclease

gene-GBA52_021058 tRNA-splicing endonuclease subunit

gene-GBA52_023034 Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Unwinds duplex DNA. Component of the meiotic recombination pathway. Seems to play a role in mediating chromosome homology search, chromosome pairing and synapsis at early stages and probably chromosome crossing-over at later stages in meiosis. Probably is involved in the repair of meiotic double strand breaks (DBSs) and in homologous recombination

Regulatory gene

gene-GBA52_000014 NAC domain-containing protein

gene-GBA52_000358 NAC transcription factor

gene-GBA52_000447 Agamous-like MADS-box protein

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Expression Profile

DataSet	Number of Samples expressed(TPM>1)	Mean	Min	Max	Standard deviation(SD)	Coeffcient variation(CV)

Select Expression

Pathway

GO Term	Description	GO Category
GO:0003674	molecular_function	MF
GO:0003824	catalytic activity	MF
GO:0004518	nuclease activity	MF
GO:0004519	endonuclease activity	MF
GO:0006139	nucleobase-containing compound metabolic process	BP
GO:0006259	DNA metabolic process	BP
GO:0006281	DNA repair	BP
GO:0006310	DNA recombination	BP
GO:0006725	cellular aromatic compound metabolic process	BP
GO:0006807	nitrogen compound metabolic process	BP
GO:0006950	response to stress	BP
GO:0006974	cellular response to DNA damage stimulus	BP
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0009314	response to radiation	BP
GO:0009411	response to UV	BP
GO:0009416	response to light stimulus	BP
GO:0009628	response to abiotic stimulus	BP
GO:0009642	response to light intensity	BP
GO:0009644	response to high light intensity	BP
GO:0009987	cellular process	BP
GO:0010212	response to ionizing radiation	BP
GO:0010332	response to gamma radiation	BP
GO:0016787	hydrolase activity	MF
GO:0016788	hydrolase activity, acting on ester bonds	MF
GO:0033554	cellular response to stress	BP
GO:0034641	cellular nitrogen compound metabolic process	BP
GO:0043170	macromolecule metabolic process	BP
GO:0044237	cellular metabolic process	BP
GO:0044238	primary metabolic process	BP
GO:0044260	cellular macromolecule metabolic process	BP
GO:0046483	heterocycle metabolic process	BP
GO:0050896	response to stimulus	BP
GO:0051716	cellular response to stimulus	BP
GO:0071704	organic substance metabolic process	BP
GO:0090304	nucleic acid metabolic process	BP
GO:0090305	nucleic acid phosphodiester bond hydrolysis	BP
GO:1901360	organic cyclic compound metabolic process	BP

KEGG Term	Name	Description
map03440	Homologous recombination	Homologous recombination (HR) is essential for the accurate repair of DNA double-strand breaks (DSBs), potentially lethal lesions. HR takes place in the late S-G2 phase of the cell cycle and involves the generation of a single-stranded region of DNA, followed by strand invasion, formation of a Holliday junction, DNA synthesis using the intact strand as a template, branch migration and resolution. It is investigated that RecA/Rad51 family proteins play a central role. The breast cancer susceptibility protein Brca2 and the RecQ helicase BLM (Bloom syndrome mutated) are tumor suppressors that maintain genome integrity, at least in part, through HR.