Basic Information
Gene Structure
Domain
Regulation&
Interaction
Annotation
Orthologus Group
Expresssion
Pathway
Basic Information
Gene ID
PSME_24116.g
Position
jcf7190000276032:6900-13438 (-)
6538bp
Gene Type
gene
Gene Description (Protein Product)
to Saccharomyces cerevisiae GCN2 (YDR283C)
Organism
Pseudotsuga menziesii
Also AS AT3G59410

Gene Structure

upstream:
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Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
PSME_33433.g to Saccharomyces cerevisiae ASC1 (YMR116C)
PSME_24116.g to Saccharomyces cerevisiae GCN2 (YDR283C)
PSME_34034.g Belongs to the universal ribosomal protein uS8 family

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail

Expression Profile
DataSet Number of Samples expressed(TPM>1) Mean Min Max Standard deviation(SD) Coeffcient variation(CV)


Pathway
Go Pathway KEGG Pathway
GO Term Description GO Category
GO:0000049 tRNA binding MF
GO:0000075 cell cycle checkpoint signaling BP
GO:0000077 DNA damage checkpoint signaling BP
GO:0000166 nucleotide binding MF
GO:0000278 mitotic cell cycle BP
GO:0000302 response to reactive oxygen species BP
GO:0001300 obsolete chronological cell aging BP
GO:0003674 molecular_function MF
GO:0003676 nucleic acid binding MF
GO:0003723 RNA binding MF
GO:0003824 catalytic activity MF
GO:0004672 protein kinase activity MF
GO:0004674 protein serine/threonine kinase activity MF
GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity MF
GO:0005488 binding MF
GO:0005524 ATP binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005737 cytoplasm CC
GO:0005829 cytosol CC
GO:0005840 ribosome CC
GO:0006417 regulation of translation BP
GO:0006446 regulation of translational initiation BP
GO:0006464 protein modification process BP
GO:0006468 protein phosphorylation BP
GO:0006793 phosphorus metabolic process BP
GO:0006796 phosphate-containing compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006950 response to stress BP
GO:0006974 cellular response to DNA damage stimulus BP
GO:0006979 response to oxidative stress BP
GO:0007049 cell cycle BP
GO:0007050 regulation of cell cycle BP
GO:0007093 mitotic cell cycle checkpoint signaling BP
GO:0007154 cell communication BP
GO:0007165 signal transduction BP
GO:0007346 regulation of mitotic cell cycle BP
GO:0007568 aging BP
GO:0007569 obsolete cell aging BP
GO:0008144 obsolete drug binding MF
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009267 cellular response to starvation BP
GO:0009268 response to pH BP
GO:0009314 response to radiation BP
GO:0009411 response to UV BP
GO:0009416 response to light stimulus BP
GO:0009605 response to external stimulus BP
GO:0009628 response to abiotic stimulus BP
GO:0009636 response to toxic substance BP
GO:0009719 response to endogenous stimulus BP
GO:0009889 regulation of biosynthetic process BP
GO:0009890 negative regulation of biosynthetic process BP
GO:0009892 negative regulation of metabolic process BP
GO:0009987 cellular process BP
GO:0009991 response to extracellular stimulus BP
GO:0010033 response to organic substance BP
GO:0010035 response to inorganic substance BP
GO:0010243 response to organonitrogen compound BP
GO:0010447 response to acidic pH BP
GO:0010468 regulation of gene expression BP
GO:0010556 regulation of macromolecule biosynthetic process BP
GO:0010558 negative regulation of macromolecule biosynthetic process BP
GO:0010564 regulation of cell cycle process BP
GO:0010605 negative regulation of macromolecule metabolic process BP
GO:0010608 post-transcriptional regulation of gene expression BP
GO:0010629 negative regulation of gene expression BP
GO:0010646 regulation of cell communication BP
GO:0010647 positive regulation of cell communication BP
GO:0010948 negative regulation of cell cycle process BP
GO:0010998 regulation of translational initiation by eIF2 alpha phosphorylation BP
GO:0014070 response to organic cyclic compound BP
GO:0016301 kinase activity MF
GO:0016310 phosphorylation BP
GO:0016740 transferase activity MF
GO:0016772 transferase activity, transferring phosphorus-containing groups MF
GO:0016773 phosphotransferase activity, alcohol group as acceptor MF
GO:0017076 purine nucleotide binding MF
GO:0017148 negative regulation of translation BP
GO:0019222 regulation of metabolic process BP
GO:0019538 protein metabolic process BP
GO:0022402 cell cycle process BP
GO:0022626 cytosolic ribosome CC
GO:0023052 signaling BP
GO:0030554 adenyl nucleotide binding MF
GO:0031323 regulation of cellular metabolic process BP
GO:0031324 negative regulation of cellular metabolic process BP
GO:0031326 regulation of cellular biosynthetic process BP
GO:0031327 negative regulation of cellular biosynthetic process BP
GO:0031570 DNA integrity checkpoint signaling BP
GO:0031571 mitotic G1 DNA damage checkpoint signaling BP
GO:0031667 response to nutrient levels BP
GO:0031668 cellular response to extracellular stimulus BP
GO:0031669 cellular response to nutrient levels BP
GO:0032055 negative regulation of translation in response to stress BP
GO:0032057 negative regulation of translational initiation in response to stress BP
GO:0032101 regulation of response to external stimulus BP
GO:0032103 positive regulation of response to external stimulus BP
GO:0032104 regulation of response to extracellular stimulus BP
GO:0032106 positive regulation of response to extracellular stimulus BP
GO:0032107 regulation of response to nutrient levels BP
GO:0032109 positive regulation of response to nutrient levels BP
GO:0032268 regulation of protein metabolic process BP
GO:0032269 negative regulation of protein metabolic process BP
GO:0032502 developmental process BP
GO:0032553 ribonucleotide binding MF
GO:0032555 purine ribonucleotide binding MF
GO:0032559 adenyl ribonucleotide binding MF
GO:0032991 protein-containing complex CC
GO:0033554 cellular response to stress BP
GO:0034198 cellular response to amino acid starvation BP
GO:0034248 regulation of amide metabolic process BP
GO:0034249 negative regulation of amide metabolic process BP
GO:0034599 cellular response to oxidative stress BP
GO:0034614 cellular response to reactive oxygen species BP
GO:0034644 cellular response to UV BP
GO:0035556 intracellular signal transduction BP
GO:0035639 purine ribonucleoside triphosphate binding MF
GO:0035690 cellular response to xenobiotic stimulus BP
GO:0036094 small molecule binding MF
GO:0036211 protein modification process BP
GO:0042221 response to chemical BP
GO:0042493 response to xenobiotic stimulus BP
GO:0042542 response to hydrogen peroxide BP
GO:0042594 response to starvation BP
GO:0042770 signal transduction in response to DNA damage BP
GO:0043167 ion binding MF
GO:0043168 anion binding MF
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043228 non-membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043232 intracellular non-membrane-bounded organelle CC
GO:0043412 macromolecule modification BP
GO:0043555 regulation of translation in response to stress BP
GO:0043558 regulation of translational initiation in response to stress BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044267 protein metabolic process BP
GO:0044424 obsolete intracellular part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044445 obsolete cytosolic part CC
GO:0044464 obsolete cell part CC
GO:0044773 mitotic DNA damage checkpoint signaling BP
GO:0044774 mitotic DNA integrity checkpoint signaling BP
GO:0044783 mitotic G1 DNA damage checkpoint signaling BP
GO:0044819 mitotic G1/S transition checkpoint signaling BP
GO:0045182 translation regulator activity MF
GO:0045786 negative regulation of cell cycle BP
GO:0045930 negative regulation of mitotic cell cycle BP
GO:0045947 negative regulation of translational initiation BP
GO:0046677 response to antibiotic BP
GO:0046777 protein autophosphorylation BP
GO:0048518 positive regulation of biological process BP
GO:0048519 negative regulation of biological process BP
GO:0048522 positive regulation of cellular process BP
GO:0048523 negative regulation of cellular process BP
GO:0048583 regulation of response to stimulus BP
GO:0048584 positive regulation of response to stimulus BP
GO:0048869 cellular developmental process BP
GO:0050789 regulation of biological process BP
GO:0050794 regulation of cellular process BP
GO:0050896 response to stimulus BP
GO:0051171 regulation of nitrogen compound metabolic process BP
GO:0051172 negative regulation of nitrogen compound metabolic process BP
GO:0051246 regulation of protein metabolic process BP
GO:0051248 negative regulation of protein metabolic process BP
GO:0051716 cellular response to stimulus BP
GO:0051726 regulation of cell cycle BP
GO:0060255 regulation of macromolecule metabolic process BP
GO:0060992 response to fungicide BP
GO:0065007 biological regulation BP
GO:0070301 cellular response to hydrogen peroxide BP
GO:0070887 cellular response to chemical stimulus BP
GO:0071214 cellular response to abiotic stimulus BP
GO:0071236 cellular response to antibiotic BP
GO:0071310 cellular response to organic substance BP
GO:0071407 cellular response to organic cyclic compound BP
GO:0071417 cellular response to organonitrogen compound BP
GO:0071467 cellular response to pH BP
GO:0071468 cellular response to acidic pH BP
GO:0071478 cellular response to radiation BP
GO:0071482 cellular response to light stimulus BP
GO:0071495 cellular response to endogenous stimulus BP
GO:0071496 cellular response to external stimulus BP
GO:0071704 organic substance metabolic process BP
GO:0071849 obsolete G1 cell cycle arrest in response to nitrogen starvation BP
GO:0072395 cell cycle checkpoint signaling BP
GO:0072401 DNA integrity checkpoint signaling BP
GO:0072413 mitotic cell cycle checkpoint signaling BP
GO:0072422 DNA damage checkpoint signaling BP
GO:0072431 mitotic G1 DNA damage checkpoint signaling BP
GO:0072755 cellular response to benomyl BP
GO:0080090 regulation of primary metabolic process BP
GO:0080134 regulation of response to stress BP
GO:0080135 regulation of cellular response to stress BP
GO:0097159 organic cyclic compound binding MF
GO:0097237 cellular response to toxic substance BP
GO:0097367 carbohydrate derivative binding MF
GO:0104004 cellular response to environmental stimulus BP
GO:0140096 catalytic activity, acting on a protein MF
GO:1901265 nucleoside phosphate binding MF
GO:1901363 heterocyclic compound binding MF
GO:1901561 response to benomyl BP
GO:1901564 organonitrogen compound metabolic process BP
GO:1901698 response to nitrogen compound BP
GO:1901699 cellular response to nitrogen compound BP
GO:1901700 response to oxygen-containing compound BP
GO:1901701 cellular response to oxygen-containing compound BP
GO:1901987 regulation of cell cycle phase transition BP
GO:1901988 negative regulation of cell cycle phase transition BP
GO:1901990 regulation of mitotic cell cycle phase transition BP
GO:1901991 negative regulation of mitotic cell cycle phase transition BP
GO:1902400 mitotic G1 DNA damage checkpoint signaling BP
GO:1902402 mitotic DNA damage checkpoint signaling BP
GO:1902403 mitotic DNA integrity checkpoint signaling BP
GO:1902806 regulation of cell cycle G1/S phase transition BP
GO:1902807 negative regulation of cell cycle G1/S phase transition BP
GO:1903047 mitotic cell cycle process BP
GO:1903832 regulation of cellular response to amino acid starvation BP
GO:1903833 positive regulation of cellular response to amino acid starvation BP
GO:1904803 regulation of translation involved in cellular response to UV BP
GO:1990451 cellular stress response to acidic pH BP
GO:1990497 regulation of cytoplasmic translation in response to stress BP
GO:1990611 regulation of cytoplasmic translational initiation in response to stress BP
GO:1990625 negative regulation of cytoplasmic translational initiation in response to stress BP
GO:1990904 ribonucleoprotein complex CC
GO:1990928 response to amino acid starvation BP
GO:2000045 regulation of G1/S transition of mitotic cell cycle BP
GO:2000112 regulation of cellular macromolecule biosynthetic process BP
GO:2000113 negative regulation of cellular macromolecule biosynthetic process BP
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle BP
GO:2000765 regulation of cytoplasmic translation BP
GO:2000766 negative regulation of cytoplasmic translation BP
KEGG Term Name Description
map04141 Protein processing in endoplasmic reticulum The endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylated. Correctly folded proteins are packaged into transport vesicles that shuttle them to the Golgi complex. Misfolded proteins are retained within the ER lumen in complex with molecular chaperones. Proteins that are terminally misfolded bind to BiP and are directed toward degradation through the proteasome in a process called ER-associated degradation (ERAD). Accumulation of misfolded proteins in the ER causes ER stress and activates a signaling pathway called the unfolded protein response (UPR). In certain severe situations, however, the protective mechanisms activated by the UPR are not sufficient to restore normal ER function and cells die by apoptosis.