Basic Information
Gene Structure
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Domain
| Database | EntryID | E-Value | Start | end | InterPro ID | Description |
|---|
Regulation&Interaction
Annotation
Orthologous Group
| Orthologous ID | Species Number | All hits in PereRegDB | Hits of this species | Orthologous Detail |
|---|
Expression Profile
| DataSet | Number of Samples expressed(TPM>1) | Mean | Min | Max | Standard deviation(SD) | Coeffcient variation(CV) |
|---|
Pathway
| GO Term | Description | GO Category |
|---|---|---|
| GO:0000011 | vacuole inheritance | BP |
| GO:0003674 | molecular_function | MF |
| GO:0005488 | binding | MF |
| GO:0005515 | protein binding | MF |
| GO:0005543 | phospholipid binding | MF |
| GO:0005575 | cellular_component | CC |
| GO:0005622 | intracellular anatomical structure | CC |
| GO:0005623 | obsolete cell | CC |
| GO:0005634 | nucleus | CC |
| GO:0005737 | cytoplasm | CC |
| GO:0005768 | endosome | CC |
| GO:0006810 | transport | BP |
| GO:0006887 | exocytosis | BP |
| GO:0006892 | post-Golgi vesicle-mediated transport | BP |
| GO:0006895 | Golgi to endosome transport | BP |
| GO:0006896 | Golgi to vacuole transport | BP |
| GO:0006897 | endocytosis | BP |
| GO:0006904 | vesicle docking involved in exocytosis | BP |
| GO:0006906 | vesicle fusion | BP |
| GO:0006996 | organelle organization | BP |
| GO:0007033 | vacuole organization | BP |
| GO:0007034 | vacuolar transport | BP |
| GO:0008150 | biological_process | BP |
| GO:0008289 | lipid binding | MF |
| GO:0009987 | cellular process | BP |
| GO:0010008 | endosome membrane | CC |
| GO:0010009 | cytoplasmic side of endosome membrane | CC |
| GO:0012505 | endomembrane system | CC |
| GO:0016020 | membrane | CC |
| GO:0016043 | cellular component organization | BP |
| GO:0016050 | vesicle organization | BP |
| GO:0016192 | vesicle-mediated transport | BP |
| GO:0016482 | cytosolic transport | BP |
| GO:0017016 | small GTPase binding | MF |
| GO:0017137 | small GTPase binding | MF |
| GO:0019899 | enzyme binding | MF |
| GO:0022406 | membrane docking | BP |
| GO:0031090 | organelle membrane | CC |
| GO:0031267 | small GTPase binding | MF |
| GO:0031410 | cytoplasmic vesicle | CC |
| GO:0031982 | vesicle | CC |
| GO:0032266 | phosphatidylinositol-3-phosphate binding | MF |
| GO:0032940 | secretion by cell | BP |
| GO:0034058 | endosomal vesicle fusion | BP |
| GO:0035091 | phosphatidylinositol binding | MF |
| GO:0043167 | ion binding | MF |
| GO:0043168 | anion binding | MF |
| GO:0043226 | organelle | CC |
| GO:0043227 | membrane-bounded organelle | CC |
| GO:0043229 | intracellular organelle | CC |
| GO:0043231 | intracellular membrane-bounded organelle | CC |
| GO:0044422 | obsolete organelle part | CC |
| GO:0044424 | obsolete intracellular part | CC |
| GO:0044425 | obsolete membrane part | CC |
| GO:0044433 | obsolete cytoplasmic vesicle part | CC |
| GO:0044440 | obsolete endosomal part | CC |
| GO:0044444 | obsolete cytoplasmic part | CC |
| GO:0044446 | obsolete intracellular organelle part | CC |
| GO:0044464 | obsolete cell part | CC |
| GO:0046903 | secretion | BP |
| GO:0046907 | intracellular transport | BP |
| GO:0048193 | Golgi vesicle transport | BP |
| GO:0048278 | vesicle docking | BP |
| GO:0048284 | organelle fusion | BP |
| GO:0048308 | organelle inheritance | BP |
| GO:0051020 | GTPase binding | MF |
| GO:0051179 | localization | BP |
| GO:0051234 | establishment of localization | BP |
| GO:0051640 | organelle localization | BP |
| GO:0051641 | cellular localization | BP |
| GO:0051649 | establishment of localization in cell | BP |
| GO:0061024 | membrane organization | BP |
| GO:0061025 | membrane fusion | BP |
| GO:0071840 | cellular component organization or biogenesis | BP |
| GO:0090174 | organelle membrane fusion | BP |
| GO:0097708 | intracellular vesicle | CC |
| GO:0098552 | side of membrane | CC |
| GO:0098562 | cytoplasmic side of membrane | CC |
| GO:0098588 | bounding membrane of organelle | CC |
| GO:0098657 | import into cell | BP |
| GO:0098805 | membrane | CC |
| GO:0140029 | exocytic process | BP |
| GO:0140056 | organelle localization by membrane tethering | BP |
| GO:1901981 | phosphatidylinositol phosphate binding | MF |
| KEGG Term | Name | Description |
|---|---|---|
| map04144 | Endocytosis | Endocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins entering through clathrin-dependent endocytosis (CDE) have sequences in their cytoplasmic domains that bind to the APs (adaptor-related protein complexes) and enable their rapid removal from the PM. In addition to APs and clathrin, there are numerous accessory proteins including dynamin. Depending on the various proteins that enter the endosome membrane, these cargoes are sorted to distinct destinations. Some cargoes, such as nutrient receptors, are recycled back to the PM. Ubiquitylated membrane proteins, such as activated growth-factor receptors, are sorted into intraluminal vesicles and eventually end up in the lysosome lumen via multivesicular endosomes (MVEs). There are distinct mechanisms of clathrin-independent endocytosis (CIE) depending upon the cargo and the cell type. |

