Basic Information
Gene ID
gene-IMY05_C4401000900
Position
JAEQKX010000643.1:23991-25965 (-)
1974bp
Gene Type
gene
Gene Description (Protein Product)
Fumarate hydratase
Organism
Also AS AT2G47510

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
gene-IMY05_C4610000100 Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q)
gene-IMY05_C4491000100 Belongs to the citrate synthase family
gene-IMY05_C4805000200 Aminotransferase class I and II

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
GO Term Description GO Category
GO:0003674 molecular_function MF
GO:0003824 catalytic activity MF
GO:0004333 fumarate hydratase activity MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005737 cytoplasm CC
GO:0005739 mitochondrion CC
GO:0005759 mitochondrial matrix CC
GO:0005829 cytosol CC
GO:0006082 organic acid metabolic process BP
GO:0006091 generation of precursor metabolites and energy BP
GO:0006099 tricarboxylic acid cycle BP
GO:0006101 citrate metabolic process BP
GO:0006106 fumarate metabolic process BP
GO:0006108 malate metabolic process BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009060 aerobic respiration BP
GO:0009987 cellular process BP
GO:0015980 energy derivation by oxidation of organic compounds BP
GO:0016829 lyase activity MF
GO:0016835 carbon-oxygen lyase activity MF
GO:0016836 hydro-lyase activity MF
GO:0016999 antibiotic metabolic process BP
GO:0017144 xenobiotic metabolic process BP
GO:0019752 carboxylic acid metabolic process BP
GO:0031974 membrane-enclosed lumen CC
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043233 organelle lumen CC
GO:0043436 oxoacid metabolic process BP
GO:0043648 dicarboxylic acid metabolic process BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044281 small molecule metabolic process BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044429 obsolete mitochondrial part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044464 obsolete cell part CC
GO:0045333 cellular respiration BP
GO:0055114 obsolete oxidation-reduction process BP
GO:0070013 intracellular organelle lumen CC
GO:0071704 organic substance metabolic process BP
GO:0072350 tricarboxylic acid metabolic process BP
KEGG Term Name Description
map01110 Biosynthesis of secondary metabolites -
map01100 Metabolic pathways -
map00620 Pyruvate metabolism -
map00020 Citrate cycle (TCA cycle) The citrate cycle (TCA cycle, Krebs cycle) is an important aerobic pathway for the final steps of the oxidation of carbohydrates and fatty acids. The cycle starts with acetyl-CoA, the activated form of acetate, derived from glycolysis and pyruvate oxidation for carbohydrates and from beta oxidation of fatty acids. The two-carbon acetyl group in acetyl-CoA is transferred to the four-carbon compound of oxaloacetate to form the six-carbon compound of citrate. In a series of reactions two carbons in citrate are oxidized to CO2 and the reaction pathway supplies NADH for use in the oxidative phosphorylation and other metabolic processes. The pathway also supplies important precursor metabolites including 2-oxoglutarate. At the end of the cycle the remaining four-carbon part is transformed back to oxaloacetate. According to the genome sequence data, many organisms seem to lack genes for the full cycle [MD:M00009], but contain genes for specific segments [MD:M00010 M00011].