PPGR - Gene Detail

Basic Information

Gene Structure

Domain

Regulation&
Interaction

Annotation

Orthologus Group

Pathway

Basic Information

Gene ID	gene-IMY05_C4462000200 View in Genome Browser
Position	JAEQKX010000674.1:11401-12980 (+) 1579bp
Gene Type	gene
Gene Description (Protein Product)	AAA domain
Organism	Salix suchowensis
Also AS	AT1G08840

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)

gene-IMY05_C4857000200 Belongs to the helicase family. RecQ subfamily

gene-IMY05_C4931000200 ATP-dependent DNA helicase

gene-IMY05_C4891000100 four-way junction helicase activity

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Pathway

GO Term	Description	GO Category
GO:0000003	reproduction	BP
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	MF
GO:0000166	nucleotide binding	MF
GO:0000228	nuclear chromosome	CC
GO:0000278	mitotic cell cycle	BP
GO:0000706	meiotic DNA double-strand break processing	BP
GO:0000723	telomere maintenance	BP
GO:0000729	DNA double-strand break processing	BP
GO:0000733	obsolete DNA strand renaturation	BP
GO:0000781	chromosome, telomeric region	CC
GO:0000784	chromosome, telomeric region	CC
GO:0001302	obsolete replicative cell aging	BP
GO:0003674	molecular_function	MF
GO:0003678	DNA helicase activity	MF
GO:0003682	chromatin binding	MF
GO:0003824	catalytic activity	MF
GO:0004003	DNA helicase activity	MF
GO:0004386	helicase activity	MF
GO:0004518	nuclease activity	MF
GO:0004519	endonuclease activity	MF
GO:0004520	DNA endonuclease activity	MF
GO:0004527	exonuclease activity	MF
GO:0004529	DNA exonuclease activity	MF
GO:0004536	deoxyribonuclease activity	MF
GO:0005488	binding	MF
GO:0005515	protein binding	MF
GO:0005524	ATP binding	MF
GO:0005575	cellular_component	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005634	nucleus	CC
GO:0005654	nucleoplasm	CC
GO:0005657	replication fork	CC
GO:0005694	chromosome	CC
GO:0005737	cytoplasm	CC
GO:0006139	nucleobase-containing compound metabolic process	BP
GO:0006259	DNA metabolic process	BP
GO:0006260	DNA replication	BP
GO:0006261	DNA-templated DNA replication	BP
GO:0006271	DNA strand elongation involved in DNA replication	BP
GO:0006273	lagging strand elongation	BP
GO:0006281	DNA repair	BP
GO:0006302	double-strand break repair	BP
GO:0006401	RNA catabolic process	BP
GO:0006725	cellular aromatic compound metabolic process	BP
GO:0006807	nitrogen compound metabolic process	BP
GO:0006950	response to stress	BP
GO:0006974	cellular response to DNA damage stimulus	BP
GO:0006996	organelle organization	BP
GO:0007049	cell cycle	BP
GO:0007568	aging	BP
GO:0007569	obsolete cell aging	BP
GO:0008026	helicase activity	MF
GO:0008094	ATP-dependent activity, acting on DNA	MF
GO:0008144	obsolete drug binding	MF
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	MF
GO:0008409	5'-3' exonuclease activity	MF
GO:0009056	catabolic process	BP
GO:0009057	macromolecule catabolic process	BP
GO:0009058	biosynthetic process	BP
GO:0009059	macromolecule biosynthetic process	BP
GO:0009607	response to biotic stimulus	BP
GO:0009719	response to endogenous stimulus	BP
GO:0009987	cellular process	BP
GO:0016043	cellular component organization	BP
GO:0016070	RNA metabolic process	BP
GO:0016233	telomere capping	BP
GO:0016462	pyrophosphatase activity	MF
GO:0016787	hydrolase activity	MF
GO:0016788	hydrolase activity, acting on ester bonds	MF
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	MF
GO:0016817	hydrolase activity, acting on acid anhydrides	MF
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	MF
GO:0016887	ATP hydrolysis activity	MF
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	MF
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	MF
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	MF
GO:0017076	purine nucleotide binding	MF
GO:0017108	5'-flap endonuclease activity	MF
GO:0017111	ribonucleoside triphosphate phosphatase activity	MF
GO:0019439	aromatic compound catabolic process	BP
GO:0019899	enzyme binding	MF
GO:0019900	kinase binding	MF
GO:0019901	protein kinase binding	MF
GO:0022402	cell cycle process	BP
GO:0022414	reproductive process	BP
GO:0022616	DNA strand elongation	BP
GO:0030554	adenyl nucleotide binding	MF
GO:0031297	replication fork processing	BP
GO:0031860	telomeric 3' overhang formation	BP
GO:0031974	membrane-enclosed lumen	CC
GO:0031981	nuclear lumen	CC
GO:0032200	telomere organization	BP
GO:0032392	DNA geometric change	BP
GO:0032502	developmental process	BP
GO:0032508	DNA duplex unwinding	BP
GO:0032553	ribonucleotide binding	MF
GO:0032555	purine ribonucleotide binding	MF
GO:0032559	adenyl ribonucleotide binding	MF
GO:0033260	nuclear DNA replication	BP
GO:0033554	cellular response to stress	BP
GO:0033567	DNA replication, Okazaki fragment processing	BP
GO:0034641	cellular nitrogen compound metabolic process	BP
GO:0034645	cellular macromolecule biosynthetic process	BP
GO:0034655	nucleobase-containing compound catabolic process	BP
GO:0035312	5'-3' DNA exonuclease activity	MF
GO:0035639	purine ribonucleoside triphosphate binding	MF
GO:0035861	site of double-strand break	CC
GO:0036094	small molecule binding	MF
GO:0042592	homeostatic process	BP
GO:0042623	ATP hydrolysis activity	MF
GO:0043137	DNA replication, removal of RNA primer	BP
GO:0043167	ion binding	MF
GO:0043168	anion binding	MF
GO:0043170	macromolecule metabolic process	BP
GO:0043226	organelle	CC
GO:0043227	membrane-bounded organelle	CC
GO:0043228	non-membrane-bounded organelle	CC
GO:0043229	intracellular organelle	CC
GO:0043231	intracellular membrane-bounded organelle	CC
GO:0043232	intracellular non-membrane-bounded organelle	CC
GO:0043233	organelle lumen	CC
GO:0043596	nuclear replication fork	CC
GO:0044237	cellular metabolic process	BP
GO:0044238	primary metabolic process	BP
GO:0044248	cellular catabolic process	BP
GO:0044249	cellular biosynthetic process	BP
GO:0044260	cellular macromolecule metabolic process	BP
GO:0044265	cellular macromolecule catabolic process	BP
GO:0044270	cellular nitrogen compound catabolic process	BP
GO:0044422	obsolete organelle part	CC
GO:0044424	obsolete intracellular part	CC
GO:0044427	obsolete chromosomal part	CC
GO:0044428	obsolete nuclear part	CC
GO:0044446	obsolete intracellular organelle part	CC
GO:0044454	obsolete nuclear chromosome part	CC
GO:0044464	obsolete cell part	CC
GO:0044786	cell cycle DNA replication	BP
GO:0045005	DNA-templated DNA replication maintenance of fidelity	BP
GO:0045145	single-stranded DNA 5'-3' DNA exonuclease activity	MF
GO:0046483	heterocycle metabolic process	BP
GO:0046700	heterocycle catabolic process	BP
GO:0048256	flap endonuclease activity	MF
GO:0048869	cellular developmental process	BP
GO:0050896	response to stimulus	BP
GO:0051276	chromosome organization	BP
GO:0051321	meiotic cell cycle	BP
GO:0051716	cellular response to stimulus	BP
GO:0060249	anatomical structure homeostasis	BP
GO:0065007	biological regulation	BP
GO:0065008	regulation of biological quality	BP
GO:0070013	intracellular organelle lumen	CC
GO:0070035	obsolete purine NTP-dependent helicase activity	MF
GO:0071103	DNA conformation change	BP
GO:0071216	cellular response to biotic stimulus	BP
GO:0071495	cellular response to endogenous stimulus	BP
GO:0071704	organic substance metabolic process	BP
GO:0071840	cellular component organization or biogenesis	BP
GO:0071932	replication fork reversal	BP
GO:0072396	response to cell cycle checkpoint signaling	BP
GO:0072402	response to DNA integrity checkpoint signaling	BP
GO:0072423	response to DNA damage checkpoint signaling	BP
GO:0072429	response to intra-S DNA damage checkpoint signaling	BP
GO:0090304	nucleic acid metabolic process	BP
GO:0090305	nucleic acid phosphodiester bond hydrolysis	BP
GO:0090734	site of DNA damage	CC
GO:0097159	organic cyclic compound binding	MF
GO:0097367	carbohydrate derivative binding	MF
GO:0098687	chromosomal region	CC
GO:0140097	catalytic activity, acting on DNA	MF
GO:1901265	nucleoside phosphate binding	MF
GO:1901360	organic cyclic compound metabolic process	BP
GO:1901361	organic cyclic compound catabolic process	BP
GO:1901363	heterocyclic compound binding	MF
GO:1901575	organic substance catabolic process	BP
GO:1901576	organic substance biosynthetic process	BP
GO:1902969	mitotic DNA replication	BP
GO:1903046	meiotic cell cycle process	BP
GO:1903047	mitotic cell cycle process	BP
GO:1903461	Okazaki fragment processing involved in mitotic DNA replication	BP
GO:1903469	removal of RNA primer involved in mitotic DNA replication	BP
GO:1990601	5' overhang single-stranded DNA endodeoxyribonuclease activity	MF

KEGG Term	Name	Description
map03030	DNA replication	A complex network of interacting proteins and enzymes is required for DNA replication. Generally, DNA replication follows a multistep enzymatic pathway. At the DNA replication fork, a DNA helicase (DnaB or MCM complex) precedes the DNA synthetic machinery and unwinds the duplex parental DNA in cooperation with the SSB or RPA. On the leading strand, replication occurs continuously in a 5 to 3 direction, whereas on the lagging strand, DNA replication occurs discontinuously by synthesis and joining of short Okazaki fragments. In prokaryotes, the leading strand replication apparatus consists of a DNA polymerase (pol III core), a sliding clamp (beta), and a clamp loader (gamma delta complex). The DNA primase (DnaG) is needed to form RNA primers. Normally, during replication of the lagging-strand DNA template, an RNA primer is removed either by an RNase H or by the 5 to 3 exonuclease activity of DNA pol I, and the DNA ligase joins the Okazaki fragments. In eukaryotes, three DNA polymerases (alpha, delta, and epsilon) have been identified. DNA primase forms a permanent complex with DNA polymerase alpha. PCNA and RFC function as a clamp and a clamp loader. FEN 1 and RNase H1 remove the RNA from the Okazaki fragments and DNA ligase I joins the DNA.