Basic Information
Gene ID
gene-IMY05_C4524000500
Position
JAEQKX010000733.1:13016-14238 (+)
1222bp
Gene Type
gene
Gene Description (Protein Product)
DnaJ central domain
Organism
Also AS AT5G22060

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
gene-IMY05_C4824000100 heat shock protein 70
gene-IMY05_C4827000200 heat shock protein 70

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
GO Term Description GO Category
GO:0001671 ATPase activator activity MF
GO:0003674 molecular_function MF
GO:0005488 binding MF
GO:0005515 protein binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005737 cytoplasm CC
GO:0005829 cytosol CC
GO:0006403 RNA localization BP
GO:0006404 RNA import into nucleus BP
GO:0006457 protein folding BP
GO:0006458 'de novo' protein folding BP
GO:0006508 proteolysis BP
GO:0006511 ubiquitin-dependent protein catabolic process BP
GO:0006605 protein targeting BP
GO:0006626 protein targeting to mitochondrion BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006810 transport BP
GO:0006839 mitochondrial transport BP
GO:0006886 intracellular protein transport BP
GO:0006913 nucleocytoplasmic transport BP
GO:0006950 response to stress BP
GO:0006996 organelle organization BP
GO:0007005 mitochondrion organization BP
GO:0008047 enzyme activator activity MF
GO:0008104 protein localization BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009056 catabolic process BP
GO:0009057 macromolecule catabolic process BP
GO:0009987 cellular process BP
GO:0010033 response to organic substance BP
GO:0010243 response to organonitrogen compound BP
GO:0010498 proteasomal protein catabolic process BP
GO:0015031 protein transport BP
GO:0015833 peptide transport BP
GO:0015931 nucleobase-containing compound transport BP
GO:0016043 cellular component organization BP
GO:0019538 protein metabolic process BP
GO:0019941 modification-dependent protein catabolic process BP
GO:0030163 protein catabolic process BP
GO:0030234 enzyme regulator activity MF
GO:0030433 ubiquitin-dependent ERAD pathway BP
GO:0030544 Hsp70 protein binding MF
GO:0031072 heat shock protein binding MF
GO:0032781 positive regulation of ATP-dependent activity BP
GO:0032991 protein-containing complex CC
GO:0033036 macromolecule localization BP
GO:0033365 protein localization to organelle BP
GO:0033554 cellular response to stress BP
GO:0034613 protein localization BP
GO:0034976 response to endoplasmic reticulum stress BP
GO:0035719 tRNA import into nucleus BP
GO:0036503 ERAD pathway BP
GO:0042026 protein refolding BP
GO:0042221 response to chemical BP
GO:0042886 amide transport BP
GO:0043085 positive regulation of catalytic activity BP
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process BP
GO:0043170 macromolecule metabolic process BP
GO:0043462 regulation of ATP-dependent activity BP
GO:0043632 modification-dependent macromolecule catabolic process BP
GO:0044093 positive regulation of molecular function BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044248 cellular catabolic process BP
GO:0044257 protein catabolic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044265 cellular macromolecule catabolic process BP
GO:0044267 protein metabolic process BP
GO:0044424 obsolete intracellular part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044445 obsolete cytosolic part CC
GO:0044464 obsolete cell part CC
GO:0045047 protein targeting to ER BP
GO:0045184 establishment of protein localization BP
GO:0046907 intracellular transport BP
GO:0048471 perinuclear region of cytoplasm CC
GO:0048519 negative regulation of biological process BP
GO:0048523 negative regulation of cellular process BP
GO:0048583 regulation of response to stimulus BP
GO:0048585 negative regulation of response to stimulus BP
GO:0050657 nucleic acid transport BP
GO:0050658 RNA transport BP
GO:0050789 regulation of biological process BP
GO:0050790 regulation of catalytic activity BP
GO:0050794 regulation of cellular process BP
GO:0050896 response to stimulus BP
GO:0051031 tRNA transport BP
GO:0051082 unfolded protein binding MF
GO:0051169 nuclear transport BP
GO:0051170 import into nucleus BP
GO:0051179 localization BP
GO:0051234 establishment of localization BP
GO:0051236 establishment of RNA localization BP
GO:0051336 regulation of hydrolase activity BP
GO:0051345 positive regulation of hydrolase activity BP
GO:0051603 proteolysis involved in protein catabolic process BP
GO:0051641 cellular localization BP
GO:0051649 establishment of localization in cell BP
GO:0051716 cellular response to stimulus BP
GO:0060589 nucleoside-triphosphatase regulator activity MF
GO:0060590 ATPase regulator activity MF
GO:0065007 biological regulation BP
GO:0065009 regulation of molecular function BP
GO:0070585 protein localization to mitochondrion BP
GO:0070727 cellular macromolecule localization BP
GO:0070972 protein localization to endoplasmic reticulum BP
GO:0071702 organic substance transport BP
GO:0071704 organic substance metabolic process BP
GO:0071705 nitrogen compound transport BP
GO:0071840 cellular component organization or biogenesis BP
GO:0072379 ER membrane insertion complex CC
GO:0072380 TRC complex CC
GO:0072594 establishment of protein localization to organelle BP
GO:0072599 establishment of protein localization to endoplasmic reticulum BP
GO:0072655 establishment of protein localization to mitochondrion BP
GO:0080134 regulation of response to stress BP
GO:0080135 regulation of cellular response to stress BP
GO:0098772 molecular function regulator activity MF
GO:1900034 regulation of cellular response to heat BP
GO:1900035 negative regulation of cellular response to heat BP
GO:1901564 organonitrogen compound metabolic process BP
GO:1901565 organonitrogen compound catabolic process BP
GO:1901575 organic substance catabolic process BP
GO:1901698 response to nitrogen compound BP
KEGG Term Name Description
map04141 Protein processing in endoplasmic reticulum The endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylated. Correctly folded proteins are packaged into transport vesicles that shuttle them to the Golgi complex. Misfolded proteins are retained within the ER lumen in complex with molecular chaperones. Proteins that are terminally misfolded bind to BiP and are directed toward degradation through the proteasome in a process called ER-associated degradation (ERAD). Accumulation of misfolded proteins in the ER causes ER stress and activates a signaling pathway called the unfolded protein response (UPR). In certain severe situations, however, the protective mechanisms activated by the UPR are not sufficient to restore normal ER function and cells die by apoptosis.