Basic Information
Gene Structure
Domain
Regulation&
Interaction
Annotation
Orthologus Group
Expresssion
Pathway
Basic Information
Gene ID
gene-LOC107407139
View in Genome Browser
Position
NC_063291.1:10479059-10481771 (-)
2712bp
Gene Type
gene
Gene Description (Protein Product)
HhH-GPD superfamily base excision DNA repair protein
Organism
Ziziphus jujuba
Also AS AT3G47830

Gene Structure

upstream:
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Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
gene-LOC125423478 Bifunctional DNA N-glycosylase with associated apurinic apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER); the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N- glycosidic bond; leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines
gene-LOC107421847 Bifunctional DNA N-glycosylase with associated apurinic apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER); the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N- glycosidic bond; leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines
gene-LOC107434063 DEK C terminal domain
Regulatory gene
gene-LOC107403899 dof zinc finger protein
gene-LOC107404161 Zinc finger protein
gene-LOC107404189 Zinc finger CCCH domain-containing protein

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail

Expression Profile
DataSet Number of Samples expressed(TPM>1) Mean Min Max Standard deviation(SD) Coeffcient variation(CV)


Pathway
Go Pathway KEGG Pathway
GO Term Description GO Category
GO:0003674 molecular_function MF
GO:0003824 catalytic activity MF
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006259 DNA metabolic process BP
GO:0006281 DNA repair BP
GO:0006304 DNA modification BP
GO:0006305 DNA alkylation BP
GO:0006306 DNA methylation BP
GO:0006325 chromatin organization BP
GO:0006342 heterochromatin formation BP
GO:0006355 regulation of DNA-templated transcription BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006950 response to stress BP
GO:0006952 defense response BP
GO:0006974 cellular response to DNA damage stimulus BP
GO:0006996 organelle organization BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009605 response to external stimulus BP
GO:0009607 response to biotic stimulus BP
GO:0009620 response to fungus BP
GO:0009889 regulation of biosynthetic process BP
GO:0009890 negative regulation of biosynthetic process BP
GO:0009891 positive regulation of biosynthetic process BP
GO:0009892 negative regulation of metabolic process BP
GO:0009893 positive regulation of metabolic process BP
GO:0009987 cellular process BP
GO:0010468 regulation of gene expression BP
GO:0010556 regulation of macromolecule biosynthetic process BP
GO:0010557 positive regulation of macromolecule biosynthetic process BP
GO:0010558 negative regulation of macromolecule biosynthetic process BP
GO:0010604 positive regulation of macromolecule metabolic process BP
GO:0010605 negative regulation of macromolecule metabolic process BP
GO:0010628 positive regulation of gene expression BP
GO:0010629 negative regulation of gene expression BP
GO:0010639 negative regulation of organelle organization BP
GO:0016043 cellular component organization BP
GO:0016458 obsolete gene silencing BP
GO:0016787 hydrolase activity MF
GO:0016798 hydrolase activity, acting on glycosyl bonds MF
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds MF
GO:0019104 DNA N-glycosylase activity MF
GO:0019219 regulation of nucleobase-containing compound metabolic process BP
GO:0019222 regulation of metabolic process BP
GO:0031323 regulation of cellular metabolic process BP
GO:0031324 negative regulation of cellular metabolic process BP
GO:0031325 positive regulation of cellular metabolic process BP
GO:0031326 regulation of cellular biosynthetic process BP
GO:0031327 negative regulation of cellular biosynthetic process BP
GO:0031328 positive regulation of cellular biosynthetic process BP
GO:0031935 obsolete regulation of chromatin silencing BP
GO:0031936 obsolete negative regulation of chromatin silencing BP
GO:0032259 methylation BP
GO:0033043 regulation of organelle organization BP
GO:0033044 regulation of chromosome organization BP
GO:0033554 cellular response to stress BP
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0035510 DNA dealkylation BP
GO:0040029 epigenetic regulation of gene expression BP
GO:0043170 macromolecule metabolic process BP
GO:0043207 response to external biotic stimulus BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043412 macromolecule modification BP
GO:0043414 macromolecule methylation BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044424 obsolete intracellular part CC
GO:0044464 obsolete cell part CC
GO:0044728 obsolete DNA methylation or demethylation BP
GO:0045814 negative regulation of gene expression, epigenetic BP
GO:0045815 transcription initiation-coupled chromatin remodeling BP
GO:0045892 negative regulation of DNA-templated transcription BP
GO:0045893 positive regulation of DNA-templated transcription BP
GO:0045934 negative regulation of nucleobase-containing compound metabolic process BP
GO:0045935 positive regulation of nucleobase-containing compound metabolic process BP
GO:0046483 heterocycle metabolic process BP
GO:0048518 positive regulation of biological process BP
GO:0048519 negative regulation of biological process BP
GO:0048522 positive regulation of cellular process BP
GO:0048523 negative regulation of cellular process BP
GO:0050789 regulation of biological process BP
GO:0050794 regulation of cellular process BP
GO:0050832 defense response to fungus BP
GO:0050896 response to stimulus BP
GO:0051128 regulation of cellular component organization BP
GO:0051129 negative regulation of cellular component organization BP
GO:0051171 regulation of nitrogen compound metabolic process BP
GO:0051172 negative regulation of nitrogen compound metabolic process BP
GO:0051173 positive regulation of nitrogen compound metabolic process BP
GO:0051252 regulation of RNA metabolic process BP
GO:0051253 negative regulation of RNA metabolic process BP
GO:0051254 positive regulation of RNA metabolic process BP
GO:0051276 chromosome organization BP
GO:0051704 obsolete multi-organism process BP
GO:0051707 response to other organism BP
GO:0051716 cellular response to stimulus BP
GO:0060255 regulation of macromolecule metabolic process BP
GO:0060968 obsolete regulation of gene silencing BP
GO:0060969 obsolete negative regulation of gene silencing BP
GO:0065007 biological regulation BP
GO:0070988 demethylation BP
GO:0071704 organic substance metabolic process BP
GO:0071840 cellular component organization or biogenesis BP
GO:0080090 regulation of primary metabolic process BP
GO:0080111 DNA demethylation BP
GO:0090304 nucleic acid metabolic process BP
GO:0098542 defense response to other organism BP
GO:0140097 catalytic activity, acting on DNA MF
GO:1901360 organic cyclic compound metabolic process BP
GO:1902275 regulation of chromatin organization BP
GO:1902679 negative regulation of RNA biosynthetic process BP
GO:1902680 positive regulation of RNA biosynthetic process BP
GO:1903506 regulation of nucleic acid-templated transcription BP
GO:1903507 negative regulation of nucleic acid-templated transcription BP
GO:1903508 positive regulation of nucleic acid-templated transcription BP
GO:1905268 negative regulation of chromatin organization BP
GO:2000112 regulation of cellular macromolecule biosynthetic process BP
GO:2000113 negative regulation of cellular macromolecule biosynthetic process BP
GO:2001141 regulation of RNA biosynthetic process BP
GO:2001251 negative regulation of chromosome organization BP
KEGG Term Name Description
map03410 Base excision repair Base excision repair (BER) is the predominant DNA damage repair pathway for the processing of small base lesions, derived from oxidation and alkylation damages. BER is normally defined as DNA repair initiated by lesion-specific DNA glycosylases and completed by either of the two sub-pathways: short-patch BER where only one nucleotide is replaced and long-patch BER where 2-13 nucleotides are replaced. Each sub-pathway of BER relies on the formation of protein complexes that assemble at the site of the DNA lesion and facilitate repair in a coordinated fashion. This process of complex formation appears to provide an increase in specificity and efficiency to the BER pathway, thereby facilitating the maintenance of genome integrity by preventing the accumulation of highly toxic repair intermediates.