Basic Information
Gene ID
gene-LOC107430012
Position
NC_063297.1:5275375-5281061 (-)
5686bp
Gene Type
gene
Gene Description (Protein Product)
Phosphatidylinositol glycan anchor biosynthesis class U
Organism
Also AS AT1G63110

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
gene-LOC125418191 GPI transamidase component
gene-LOC125421779 Glycosylphosphatidylinositol anchor attachment 1
gene-LOC112489370 GPI biosynthesis protein family Pig-F

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail

Expression Profile
DataSet Number of Samples expressed(TPM>1) Mean Min Max Standard deviation(SD) Coeffcient variation(CV)


Pathway
GO Term Description GO Category
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005737 cytoplasm CC
GO:0005783 endoplasmic reticulum CC
GO:0005789 endoplasmic reticulum membrane CC
GO:0012505 endomembrane system CC
GO:0016020 membrane CC
GO:0016021 membrane CC
GO:0030176 obsolete integral component of endoplasmic reticulum membrane CC
GO:0031224 obsolete intrinsic component of membrane CC
GO:0031227 obsolete intrinsic component of endoplasmic reticulum membrane CC
GO:0031984 organelle subcompartment CC
GO:0032991 protein-containing complex CC
GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network CC
GO:0042765 GPI-anchor transamidase complex CC
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044425 obsolete membrane part CC
GO:0044432 obsolete endoplasmic reticulum part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044464 obsolete cell part CC
GO:0098796 membrane protein complex CC
GO:0098827 endoplasmic reticulum subcompartment CC
GO:1902494 catalytic complex CC
KEGG Term Name Description
map01100 Metabolic pathways -
map00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis Cell surface proteins can be attached to the cell membrane via the glycolipid structure called glycosylphosphatidylinositol (GPI) anchor. Hundreds of GPI-anchored proteins have been identified in many eukaryotes ranging from protozoa and fungi to mammals. All protein-linked GPI anchors share a common core structure, characterized by the substructure Man (a1-4) GlcN (a1-6) myo-inositol-1P-lipid. Biosynthesis of GPI anchors proceeds in three stages: (i) preassembly of a GPI precursor in the ER membrane, (ii) attachment of the GPI to the C-terminus of a newly synthesized protein in the lumen of the ER, and (iii) lipid remodeling and/or carbohydrate side-chain modifications in the ER and the Golgi. Defects of GPI anchor biosynthesis gene result in a genetic disorder, paroxysmal nocturnal hemoglobinuria.