PPGR - Gene Detail

Basic Information

Gene ID	gene-LOC107432321 View in Genome Browser
Position	NC_063298.1:8829200-8833768 (-) 4568bp
Gene Type	gene
Gene Description (Protein Product)	E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates
Organism	Ziziphus jujuba
Also AS	AT3G58040

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)

gene-LOC107432321 E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates

gene-LOC107435298 -

gene-LOC107435298 ethylene-responsive transcription factor

Load All Networks

Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Expression Profile

DataSet	Number of Samples expressed(TPM>1)	Mean	Min	Max	Standard deviation(SD)	Coeffcient variation(CV)

Select Expression

Pathway

GO Term	Description	GO Category
GO:0003674	molecular_function	MF
GO:0003824	catalytic activity	MF
GO:0004842	ubiquitin-protein transferase activity	MF
GO:0006464	protein modification process	BP
GO:0006807	nitrogen compound metabolic process	BP
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0009894	regulation of catabolic process	BP
GO:0009987	cellular process	BP
GO:0010506	regulation of autophagy	BP
GO:0016241	regulation of macroautophagy	BP
GO:0016567	protein ubiquitination	BP
GO:0016740	transferase activity	MF
GO:0019222	regulation of metabolic process	BP
GO:0019538	protein metabolic process	BP
GO:0019787	ubiquitin-like protein transferase activity	MF
GO:0031323	regulation of cellular metabolic process	BP
GO:0031329	regulation of cellular catabolic process	BP
GO:0032446	protein modification by small protein conjugation	BP
GO:0033043	regulation of organelle organization	BP
GO:0036211	protein modification process	BP
GO:0043170	macromolecule metabolic process	BP
GO:0043412	macromolecule modification	BP
GO:0044087	regulation of cellular component biogenesis	BP
GO:0044088	regulation of vacuole organization	BP
GO:0044237	cellular metabolic process	BP
GO:0044238	primary metabolic process	BP
GO:0044260	cellular macromolecule metabolic process	BP
GO:0044267	protein metabolic process	BP
GO:0050789	regulation of biological process	BP
GO:0050794	regulation of cellular process	BP
GO:0051128	regulation of cellular component organization	BP
GO:0061630	ubiquitin protein ligase activity	MF
GO:0061659	ubiquitin-like protein ligase activity	MF
GO:0065007	biological regulation	BP
GO:0070647	protein modification by small protein conjugation or removal	BP
GO:0071704	organic substance metabolic process	BP
GO:0140096	catalytic activity, acting on a protein	MF
GO:1901564	organonitrogen compound metabolic process	BP
GO:1902115	regulation of organelle assembly	BP
GO:2000785	regulation of autophagosome assembly	BP

KEGG Term	Name	Description
map04120	Ubiquitin mediated proteolysis	Protein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to proteins being degraded is performed by a reaction cascade consisting of three enzymes, named E1 (ubiquitin activating enzyme), E2 (ubiquitin conjugating enzyme), and E3 (ubiquitin ligase). Each E3 has specificity to its substrate, or proteins to be targeted by ubiquitination. Many E3s are discovered in eukaryotes and they are classified into four types: HECT type, U-box type, single RING-finger type, and multi-subunit RING-finger type. Multi-subunit RING-finger E3s are exemplified by cullin-Rbx E3s and APC/C. They consist of a RING-finger-containing subunit (RBX1 or RBX2) that functions to bind E2s, a scaffold-like cullin molecule, adaptor proteins, and a target recognizing subunit that binds substrates.