Basic Information
Gene Structure
Domain
Regulation&
Interaction
Annotation
Orthologus Group
Pathway
Basic Information
Gene ID
Potra2n9c19063
View in Genome Browser
Position
chr9:2985762-2991219 (-)
5457bp
Gene Type
gene
Gene Description (Protein Product)
Belongs to the AAA ATPase family
Organism
Populus tremula
Also AS Potri.009G120500AT1G45000Potri.009G120500.v4.1

Gene Structure

upstream:
Get Sequence

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
Potra2n9c19951 The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH
Potra2n9c20077 Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function
Potra2n9c19780 Ring finger

Load All Networks

Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
Go Pathway KEGG Pathway
GO Term Description GO Category
GO:0000502 proteasome complex CC
GO:0003674 molecular_function MF
GO:0003824 catalytic activity MF
GO:0005488 binding MF
GO:0005515 protein binding MF
GO:0005575 cellular_component CC
GO:0005618 cell wall CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005730 nucleolus CC
GO:0005737 cytoplasm CC
GO:0005829 cytosol CC
GO:0005838 proteasome regulatory particle CC
GO:0005886 plasma membrane CC
GO:0005911 cell-cell junction CC
GO:0006355 regulation of DNA-templated transcription BP
GO:0006357 regulation of transcription by RNA polymerase II BP
GO:0006508 proteolysis BP
GO:0006511 ubiquitin-dependent protein catabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006950 response to stress BP
GO:0008134 transcription factor binding MF
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0008540 proteasome regulatory particle, base subcomplex CC
GO:0009056 catabolic process BP
GO:0009057 macromolecule catabolic process BP
GO:0009506 plasmodesma CC
GO:0009889 regulation of biosynthetic process BP
GO:0009891 positive regulation of biosynthetic process BP
GO:0009893 positive regulation of metabolic process BP
GO:0009894 regulation of catabolic process BP
GO:0009896 positive regulation of catabolic process BP
GO:0009987 cellular process BP
GO:0010033 response to organic substance BP
GO:0010243 response to organonitrogen compound BP
GO:0010468 regulation of gene expression BP
GO:0010498 proteasomal protein catabolic process BP
GO:0010556 regulation of macromolecule biosynthetic process BP
GO:0010557 positive regulation of macromolecule biosynthetic process BP
GO:0010604 positive regulation of macromolecule metabolic process BP
GO:0010628 positive regulation of gene expression BP
GO:0016020 membrane CC
GO:0016462 pyrophosphatase activity MF
GO:0016787 hydrolase activity MF
GO:0016817 hydrolase activity, acting on acid anhydrides MF
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides MF
GO:0016887 ATP hydrolysis activity MF
GO:0017025 TBP-class protein binding MF
GO:0017111 ribonucleoside triphosphate phosphatase activity MF
GO:0019219 regulation of nucleobase-containing compound metabolic process BP
GO:0019222 regulation of metabolic process BP
GO:0019538 protein metabolic process BP
GO:0019941 modification-dependent protein catabolic process BP
GO:0022624 proteasome accessory complex CC
GO:0030054 cell junction CC
GO:0030162 regulation of proteolysis BP
GO:0030163 protein catabolic process BP
GO:0030312 external encapsulating structure CC
GO:0030433 ubiquitin-dependent ERAD pathway BP
GO:0031323 regulation of cellular metabolic process BP
GO:0031325 positive regulation of cellular metabolic process BP
GO:0031326 regulation of cellular biosynthetic process BP
GO:0031328 positive regulation of cellular biosynthetic process BP
GO:0031329 regulation of cellular catabolic process BP
GO:0031331 positive regulation of cellular catabolic process BP
GO:0031334 positive regulation of protein-containing complex assembly BP
GO:0031595 nuclear proteasome complex CC
GO:0031597 cytosolic proteasome complex CC
GO:0031974 membrane-enclosed lumen CC
GO:0031981 nuclear lumen CC
GO:0032268 regulation of protein metabolic process BP
GO:0032270 positive regulation of protein metabolic process BP
GO:0032991 protein-containing complex CC
GO:0033554 cellular response to stress BP
GO:0034976 response to endoplasmic reticulum stress BP
GO:0036402 proteasome-activating activity MF
GO:0036503 ERAD pathway BP
GO:0042176 regulation of protein catabolic process BP
GO:0042221 response to chemical BP
GO:0042623 ATP hydrolysis activity MF
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process BP
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043228 non-membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043232 intracellular non-membrane-bounded organelle CC
GO:0043233 organelle lumen CC
GO:0043254 regulation of protein-containing complex assembly BP
GO:0043632 modification-dependent macromolecule catabolic process BP
GO:0044087 regulation of cellular component biogenesis BP
GO:0044089 positive regulation of cellular component biogenesis BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044248 cellular catabolic process BP
GO:0044257 protein catabolic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044265 cellular macromolecule catabolic process BP
GO:0044267 protein metabolic process BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044428 obsolete nuclear part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044445 obsolete cytosolic part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044464 obsolete cell part CC
GO:0045732 positive regulation of protein catabolic process BP
GO:0045862 positive regulation of proteolysis BP
GO:0045893 positive regulation of DNA-templated transcription BP
GO:0045898 regulation of RNA polymerase II transcription preinitiation complex assembly BP
GO:0045899 positive regulation of RNA polymerase II transcription preinitiation complex assembly BP
GO:0045935 positive regulation of nucleobase-containing compound metabolic process BP
GO:0045944 positive regulation of transcription by RNA polymerase II BP
GO:0048518 positive regulation of biological process BP
GO:0048522 positive regulation of cellular process BP
GO:0050789 regulation of biological process BP
GO:0050794 regulation of cellular process BP
GO:0050896 response to stimulus BP
GO:0051128 regulation of cellular component organization BP
GO:0051130 positive regulation of cellular component organization BP
GO:0051171 regulation of nitrogen compound metabolic process BP
GO:0051173 positive regulation of nitrogen compound metabolic process BP
GO:0051246 regulation of protein metabolic process BP
GO:0051247 positive regulation of protein metabolic process BP
GO:0051252 regulation of RNA metabolic process BP
GO:0051254 positive regulation of RNA metabolic process BP
GO:0051603 proteolysis involved in protein catabolic process BP
GO:0051716 cellular response to stimulus BP
GO:0055044 symplast CC
GO:0060255 regulation of macromolecule metabolic process BP
GO:0060260 regulation of transcription initiation by RNA polymerase II BP
GO:0060261 positive regulation of transcription initiation by RNA polymerase II BP
GO:0061136 regulation of proteasomal protein catabolic process BP
GO:0065007 biological regulation BP
GO:0070013 intracellular organelle lumen CC
GO:0071704 organic substance metabolic process BP
GO:0071944 cell periphery CC
GO:0080090 regulation of primary metabolic process BP
GO:1901564 organonitrogen compound metabolic process BP
GO:1901565 organonitrogen compound catabolic process BP
GO:1901575 organic substance catabolic process BP
GO:1901698 response to nitrogen compound BP
GO:1901800 positive regulation of proteasomal protein catabolic process BP
GO:1902494 catalytic complex CC
GO:1902680 positive regulation of RNA biosynthetic process BP
GO:1903050 regulation of proteolysis involved in protein catabolic process BP
GO:1903052 positive regulation of proteolysis involved in protein catabolic process BP
GO:1903362 regulation of protein catabolic process BP
GO:1903364 positive regulation of protein catabolic process BP
GO:1903506 regulation of nucleic acid-templated transcription BP
GO:1903508 positive regulation of nucleic acid-templated transcription BP
GO:1905368 peptidase complex CC
GO:1905369 endopeptidase complex CC
GO:2000112 regulation of cellular macromolecule biosynthetic process BP
GO:2000142 regulation of DNA-templated transcription initiation BP
GO:2000144 positive regulation of DNA-templated transcription initiation BP
GO:2001141 regulation of RNA biosynthetic process BP
KEGG Term Name Description
map03050 Proteasome The proteasome is a protein-destroying apparatus involved in many essential cellular functions, such as regulation of cell cycle, cell differentiation, signal transduction pathways, antigen processing for appropriate immune responses, stress signaling, inflammatory responses, and apoptosis. It is capable of degrading a variety of cellular proteins in a rapid and timely fashion and most substrate proteins are modified by ubiquitin before their degradation by the proteasome. The proteasome is a large protein complex consisting of a proteolytic core called the 20S particle and ancillary factors that regulate its activity in various ways. The most common form is the 26S proteasome containing one 20S core particle and two 19S regulatory particles that enable the proteasome to degrade ubiquitinated proteins by an ATP-dependent mechanism. Another form is the immunoproteasome containing two 11S regulatory particles, PA28 alpha and PA28 beta, which are induced by interferon gamma under the conditions of intensified immune response. Other regulatory particles include PA28 gamma and PA200. Although PA28 gamma also belongs to a family of activators of the 20S proteasome, it is localized within the nucleus and forms a homoheptamer. PA28 gamma has been implicated in the regulation of cell cycle progression and apoptosis. PA200 has been identified as a large nuclear protein that stimulates proteasomal hydrolysis of peptides.